Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome

Last updated: August 19, 2022
Sponsor: University of Louisville
Overall Status: Active - Recruiting

Phase

1/2

Condition

Interstitial Cystitis

Gynecological Infections

Urinary Tract Infections

Treatment

N/A

Clinical Study ID

NCT04845217
21.0286
  • Ages 18-65
  • Female
  • Accepts Healthy Volunteers

Study Summary

The purpose of this study is to assess the use of peppermint oil as a treatment for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Women ages 18-65 years old
  • Diagnosed with IC/BPS for at least one month prior to study enrollment

Exclusion

Exclusion Criteria:

  • Culture proven urinary tract infection within 1 month of randomization
  • Gross hematuria
  • Currently pregnant or breastfeeding
  • Unable to speak and read English
  • History of allergic reaction to peppermint, coconut or enteric coating
  • History of malabsorption syndrome
  • History of gastroparesis
  • History of gastric bypass surgery
  • History of gastrointestinal, genitourinary or pelvic cancer in the last 5 years
  • History of insulin dependent diabetes
  • History of active urinary stone disease

Study Design

Total Participants: 100
Study Start date:
September 15, 2021
Estimated Completion Date:
December 31, 2023

Study Description

After being informed about the study and potential risks, all participants will complete validated IC/BPS symptom questionnaires for baseline screening. Once participants meet eligibility requirements and give written informed consent they will be randomized in a 1:1 ratio to peppermint oil (200mg TID) or placebo (also TID). Participants will complete validated IC/BPS questionnaires and follow up surveys over 8 weeks.

Connect with a study center

  • Springs Medical Center

    Louisville, Kentucky 40205
    United States

    Active - Recruiting

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