COVID-19 And Lingering Symptoms In Primary Care Patients

Last updated: August 27, 2025
Sponsor: Katarina Hedin
Overall Status: Completed

Phase

N/A

Condition

Covid-19

Treatment

N/A

Clinical Study ID

NCT04813731
2020-05448
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The ongoing corona virus disease 2019 (COVID-19) is a viral acute respiratory tract infection caused by server acute respiratory syndrom coronavirus typ 2 (SARS-CoV-2). The signs and symptom of SARS-CoV-2 infection vary and most people with COVID-19 experience illness of mild or moderate severity and recover with symptomatic treatment outside of hospital. Studies have found that some people experience lingering/long-lasting symptoms and only a minority of patients were completely free from COVID-19 related symptoms after two months. About one third still had up to two residual symptoms and 55% had three or more. As far as we know no study on lingering symptoms has been published in patients after a mild or moderate infection managed in primary care settings. The aim of this study is to explore the course of disease over a one year period and describe lingering symptoms and their impact on well-being and daily activities in adult non-hospitalized patients with previous established COVID-19 infection.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Confirmed SARS-CoV-2 infection, either by polymeras chain reaction (PCR), or byantigen testing (if authorized/recommended/used by national/local governments)

  • Symptoms consistent with mild to moderate COVID-19

  • Maximum of 2 weeks since positive SARS-CoV-2 test

  • Aged 18 years and older

  • Patient able and willing to comply with monthly phone calls.

Exclusion

Exclusion Criteria:

  • Hospitalisation due to COVID-19

Study Design

Total Participants: 300
Study Start date:
December 12, 2020
Estimated Completion Date:
June 30, 2022

Connect with a study center

  • Department of General Practice, Melbourne Medical School, University of Melbourne, Vic.

    Melbourne,
    Australia

    Site Not Available

  • Centre for General Practice, Department of Family Medicine & Population Health (FAMPOP), Faculty of Medicine and Health Sciences, University of Antwerp

    Antwerp,
    Belgium

    Site Not Available

  • Centre for General Practice, Department of Family Medicine & Population Health (FAMPOP), Faculty of Medicine and Health Sciences, University of Antwerp

    Antwerp 2803138,
    Belgium

    Site Not Available

  • the Academic Centre for General Practice (ACHG), Department of Public Health and Primary Care, KU Leuven

    Leuven,
    Belgium

    Site Not Available

  • the Academic Centre for General Practice (ACHG), Department of Public Health and Primary Care, KU Leuven

    Leuven 2792482,
    Belgium

    Site Not Available

  • Centro de Saúde "Ana Rodrigues Matoso"

    Campinas,
    Brazil

    Site Not Available

  • Center for General Practice at Aalborg University

    Aalborg,
    Denmark

    Site Not Available

  • Center for General Practice at Aalborg University

    Aalborg 2624886,
    Denmark

    Site Not Available

  • Département de Santé Publique, Université Côte d'Azur, Centre Hospitalier Universitaire de Nice, Nice, France

    Nice,
    France

    Site Not Available

  • Département de Santé Publique, Université Côte d'Azur, Centre Hospitalier Universitaire de Nice, Nice, France

    Nice 2990440,
    France

    Site Not Available

  • R. Lugar Center for Public Health Research

    Tbilisi,
    Georgia

    Site Not Available

  • R. Lugar Center for Public Health Research

    Tbilisi 611717,
    Georgia

    Site Not Available

  • Institut für Allgemeinmedizin Universitätsklinikum Würzburg Josef-Schneider-Str. 2/D7 97080 Würzburg

    Würzburg,
    Germany

    Site Not Available

  • Institut für Allgemeinmedizin Universitätsklinikum Würzburg Josef-Schneider-Str. 2/D7 97080 Würzburg

    Würzburg 2805615,
    Germany

    Site Not Available

  • School of Medicine, National University of Ireland

    Galway,
    Ireland

    Site Not Available

  • School of Medicine, National University of Ireland

    Galway 2964180,
    Ireland

    Site Not Available

  • Covid-19 primary care special unit Sassuolo, Azienda Unità Sanitaria locale di Modena, Modena, Italy

    Modena,
    Italy

    Site Not Available

  • Covid-19 primary care special unit Sassuolo, Azienda Unità Sanitaria locale di Modena, Modena, Italy

    Modena 3173331,
    Italy

    Site Not Available

  • Julius Center, University Medical Center Utrecht

    Utrecht,
    Netherlands

    Site Not Available

  • Julius Center, University Medical Center Utrecht

    Utrecht 2745912,
    Netherlands

    Site Not Available

  • Medical University of Lodz, Lodz

    Lodz 3093133,
    Poland

    Site Not Available

  • Medical University of Lodz, Lodz

    Łódź,
    Poland

    Site Not Available

  • Balan Medfam SRL

    Cluj Napoca,
    Romania

    Site Not Available

  • Balan Medfam SRL

    Cluj-Napoca 681290,
    Romania

    Site Not Available

  • Wetterhälsan Primary Health Care Centre

    Jönköping,
    Sweden

    Site Not Available

  • Wetterhälsan Primary Health Care Centre

    Jönköping 2702979,
    Sweden

    Site Not Available

  • Kärna Primary Health Care Centre

    Linköping,
    Sweden

    Site Not Available

  • Kärna Primary Health Care Centre

    Linköping 2694762,
    Sweden

    Site Not Available

  • CPHC of Mukachevo United Territorial Community, Practice Mukachevo

    Mukačeve,
    Ukraine

    Site Not Available

  • School of Medicine, University of St Andrews North Haugh, St Andrews KY16 9TF

    Saint Andrews,
    United Kingdom

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.