Evaluating the Implementation and Impact of Navigator-delivered ePRO System

Last updated: June 14, 2026
Sponsor: University of Alabama at Birmingham
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Neoplasms

Cancer

Treatment

Navigator-delivered Home ePRO

Evaluate implementation of navigator-delivered Home ePRO for all cancer patients

Clinical Study ID

NCT04809740
IRB-300007406
5R01NR019058
  • Ages > 18
  • All Genders

Study Summary

Evaluate implementation of navigator-delivered Home ePRO for all cancer patients across multiple practice sites and assess the impact of Home ePRO on clinical and utilization outcomes.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patient Group:

  • Age ≥18

  • Cancer patients at participating institution

  • Receipt of chemotherapy, targeted therapy, and immunotherapy at participatinginstitution from 2019-2026.

Exclusion

Exclusion Criteria:

  • Second opinion only at participating institution.

Study Design

Total Participants: 3090
Treatment Group(s): 2
Primary Treatment: Navigator-delivered Home ePRO
Phase:
Study Start date:
May 04, 2021
Estimated Completion Date:
February 28, 2027

Study Description

Randomized controlled trials demonstrated that weekly electronic home-based PRO symptom monitoring with automated alerts to clinicians (Home ePRO) in cancer patients was associated with reduced healthcare utilization, improved quality of life, and increased overall survival. However, these trials were administered using infrastructure supported by research funding. A knowledge gap remains about optimal implementation strategies for and effectiveness of Home ePROs in real-world settings. To address this gap, we will conduct a large-scale population-based implementation of an evidence-based Home ePRO intervention for all adult cancer patients receiving chemotherapy. The investigators' hypothesis is that the implementation of navigator-delivered Home ePRO will be successful and will improve both patient and health system outcomes.

Connect with a study center

  • University of Alabama at Birmingham

    Birmingham, Alabama 35249
    United States

    Site Not Available

  • University of Alabama at Birmingham

    Birmingham 4049979, Alabama 4829764 35249
    United States

    Active - Recruiting

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