INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit

Inclusion Criteria:

• At least 18 years of age

• Urine test positive for recent opioid use and with evidence of recent injection druguse ("track marks")

• Diagnosed with OUD per Diagnostic and Statistical Manual of Mental Disorders (DSM)-5

• Able and willing to give informed consent

• Willing to start MOUD treatment

• Able to successfully complete an Assessment of Understanding

• Self-reported sharing injection equipment and/or condomless sex in the last threemonths with partners of HIV-positive or unknown status

• Able to provide adequate locator information

• Confirmed HIV status, as defined in the HPTN 094 Study Specific Procedures Manual

Exclusion Criteria:

• Urine testing that is not negative for methadone within 30 days prior to Enrollmentis exclusionary, unless verified hospital records show methadone received as amedication for hospitalization only during the screening period. A volunteer mayprovide a sample for urine testing more than once during the screening period inorder to achieve a negative result. If this criterion cannot be met within 30 daysfrom the start of screening, the individual will be considered a screen failure andthe volunteer has up to two more screening chances to successfully complete thescreening process again.

• Received MOUD in the 30 days prior to enrollment by self-report

• Co-enrollment in any other interventional study unless approved by the ClinicalManagement Committee (CMC)