Value of the Laparoscopic Approach in the Surgical Management of Resectable Hepatocellular Carcinoma

Inclusion Criteria:

• Male or female patient aged ≥ 18 years
• Presenting with solitary or multifocal resectable HCC
• Qualifying for both pure laparoscopic and open approaches

Exclusion Criteria:

• Physical or psychological status contraindicating the participation to the study
• Contraindication to surgery
• Contraindication to pneumoperitoneum
• ASA (American Society of Anesthesiologists) score IV-V
• Life expectancy < 2 months
• Suspicion of mixed type tumor (Hepatocholangiocarcinoma) and fibrolamellar HCC
• Child-Pugh score > B7
• Extra-hepatic involvement
• Liver resection requiring an associated vascular or biliary reconstruction
• Pregnancy and breast-feeding
• Tutorship, trusteeship
• Concurrent participation in other experimental trials concerning the same objectivewithin 90 days following intervention
• No Affiliation to the French social security
• No Ability to give their consent and not written informed consent