Value of the Laparoscopic Approach in the Surgical Management of Resectable Hepatocellular Carcinoma

Inclusion Criteria:

• Male or female patient aged ≥ 18 years

• Presenting with solitary or multifocal resectable HCC

• Qualifying for both pure laparoscopic and open approaches

Exclusion Criteria:

• Physical or psychological status contraindicating the participation to the study

• Contraindication to surgery

• Contraindication to pneumoperitoneum

• ASA (American Society of Anesthesiologists) score IV-V

• Life expectancy < 2 months

• Suspicion of mixed type tumor (Hepatocholangiocarcinoma) and fibrolamellar HCC

• Child-Pugh score > B7

• Extra-hepatic involvement

• Liver resection requiring an associated vascular or biliary reconstruction

• Pregnancy and breast-feeding

• Tutorship, trusteeship

• Concurrent participation in other experimental trials concerning the same objectivewithin 90 days following intervention

• No Affiliation to the French social security

• No Ability to give their consent and not written informed consent