Long Term Follow up of the LTOG Cohort

Last updated: May 15, 2024
Sponsor: University of Pennsylvania
Overall Status: Active - Enrolling

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT04787822
834898
U01HL145435
  • Ages > 13
  • All Genders

Study Summary

The purpose of the study is to follow participants who enrolled in the Lung Transplant Outcomes Group. Clinical data, functional assessments, and surveys will be collected to determine long term graft function and functional status of lung transplant recipients.

Eligibility Criteria

Inclusion

Inclusion criteria

Long-term phenotyping of CLAD

  • Lung transplant recipients who have previously enrolled in the LTOG cohort studies at one of the participating centers

Long-term functional status and well-being

  • Lung transplant recipients who have previously enrolled in the LTOG cohort studies at one of the participating centers

  • Alive

Exclusion Criteria

Long-term phenotyping of CLAD

  • Lung transplant recipient not enrolled in LTOG cohort research studies

Long-term functional status and well-being

  • Lung transplant recipient not enrolled in the LTOG cohort research studies

  • Lung transplant recipient not receiving post-transplant follow-up care at a participating LTOG center

Study Design

Total Participants: 4000
Study Start date:
June 15, 2021
Estimated Completion Date:
May 31, 2026

Study Description

This project will involve both retrospective and prospective data collection from participants enrolled in the LTOG cohort studies. We will perform long-term Chronic Lung Allograft Dysfunction (CLAD) phenotyping of lung transplant recipients who participated in the LTOG cohort studies utilizing data collected for routine clinical visits. Surviving lung transplant recipients who participated in the LTOG cohort studies will be recruited to enroll in the longitudinal portion of the project. The longitudinal component will include follow-up data collection at 6 month intervals while alive until study termination, study withdrawal, or no longer being seen for follow-up at the participating center. Follow-up data collection will include clinical data collected by study coordinators by reviewing medical records, functional assessment through administration of the Short Physical Performance Battery (SPPB), blood collection and surveys. Data from this project will be linked to data and samples collected during the LTOG cohort or ancillary studies.

Connect with a study center

  • University of Alabama Birmingham

    Birmingham, Alabama 35294
    United States

    Site Not Available

  • University of California San Francisco

    San Francisco, California 94143
    United States

    Site Not Available

  • Stanford University

    Stanford, California 94305
    United States

    Site Not Available

  • Indiana University

    Indianapolis, Indiana 46202
    United States

    Site Not Available

  • Johns Hopkins University

    Baltimore, Maryland 21224
    United States

    Site Not Available

  • University of Michigan

    Ann Arbor, Michigan 48109
    United States

    Site Not Available

  • Columbia University

    New York, New York 10027
    United States

    Site Not Available

  • Duke University

    Durham, North Carolina 27710
    United States

    Site Not Available

  • University of Pennsylvania

    Philadelphia, Pennsylvania 19104
    United States

    Site Not Available

  • University of Pittsburgh

    Pittsburgh, Pennsylvania 15213
    United States

    Site Not Available

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