Posterior Cervical Fixation Study

Inclusion Criteria:

1. Patients who are ≥18 years of age at the time of consent

2. Have planned craniocervical, cervical (C1 to C7), and/or upper thoracic (T1-T3)spine surgery using posterior fixation planned for treatment of any of the followingconditions:

3. traumatic spinal fractures and/or traumatic dislocations

4. instability or deformity

5. failed previous fusions (e.g., pseudoarthrosis)

6. tumors involving the cervical spine

7. degenerative disease, including intractable radiculopathy and/or myelopathy,neck and/or arm pain of discogenic origin as confirmed by radiographic studies,and degenerative disease of the facets with instability

8. Using one of the following posterior occipito-cervico-thoracic fixation systems (NuVasive, Inc, San Diego, CA):

9. Vuepoint II OCT

10. Reline-C

11. Able to undergo surgery based on physical exam, medical history, and surgeonjudgment

12. Understands the conditions of enrollment and is willing to sign an informed consentform to participate in the study

Exclusion Criteria:

1. Patient is involved in active litigation relating to the spine (workers'compensation claim is allowed if it is not contested)

2. Use of bone growth stimulators postoperatively

3. Active smoking within 6 weeks of surgery

4. Patient has known sensitivity to materials implanted

5. Systemic or local infection (latent or active) or signs of local inflammation

6. Patient has inadequate bone stock or quality, or a physical or medical conditionthat would prohibit beneficial surgical outcome based on surgeon judgment

7. Pregnant, or plans to become pregnant

8. Patient is a prisoner

9. Patient is participating in another clinical study that would confound study data