Characterizing Hemorrhage in Acute Spinal Cord Injury With MRI

Last updated: June 30, 2023
Sponsor: University of British Columbia
Overall Status: Active - Recruiting

Phase

N/A

Condition

Spinal Cord Injuries

Hemorrhage

Treatment

Magnetic resonance imaging (MRI)

Clinical Study ID

NCT04758377
H20-03585
  • Ages > 19
  • All Genders

Study Summary

The study is designed to determine whether hemorrhage within the injured spinal cord is influenced by mean arterial pressure (MAP) augmentation with vasopressors and by venous thromboembolism (VTE) prophylaxis with anticoagulants in the first two weeks following a traumatic spinal cord injury (tSCI).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Acute tSCI injury involving bony spinal levels between C0 and T1
  • Baseline Asia Impairment Scale (AIS) grade of A, B, or C
  • Admission to study site within 24 hours of injury
  • Male or female age 19 or older
  • Able and willing to provide informed consent

Exclusion

Exclusion Criteria:

  • Pathological fracture due to metabolic condition or neoplasia
  • Spinal cord injury due to infection
  • Presence of pacemaker, aneurysm clip or other device which is a contraindication toMRI
  • BMI > 40 and unable to fit within the MRI scanner
  • Multiple life threatening injuries (ISS >16) that make transport to MRI not in thepatient's best interest
  • Any condition that, at the time of admission, prevents a complete ISNCSCI assessmentfrom being performed

Study Design

Total Participants: 24
Treatment Group(s): 1
Primary Treatment: Magnetic resonance imaging (MRI)
Phase:
Study Start date:
February 06, 2021
Estimated Completion Date:
June 01, 2025

Study Description

This will be a single-center prospective observational study of patients with an acute cervical traumatic spinal cord injury

Connect with a study center

  • Vancouver General Hospital

    Vancouver, British Columbia
    Canada

    Active - Recruiting

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