Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients

Inclusion Criteria:

Phase 1

• Age ≥ 18 years as per self-report

• Current or previous diagnosis of breast, ovarian, pancreatic, or prostate cancer asper self-report

• Self-identification as Black, Latino, and/or neither Black nor Latino (i.e.,non-Latino, Non black)

• Fluency in English, Haitian Creole, or Spanish as per self-report (for Spanish, wewill attempt to recruit a cohort representing a variety of regions where Spanish isspoken, as informed by current data from participating sites, to achieve neutralityin the language) Fluency is defined as an answer of "well" or "very well" on thescreening questions for spoken and reading ability.

Phase 2:

• Age ≥ 18 years as per the medical record

• Current or previous diagnosis of breast, colorectal, ovarian, pancreatic, orprostate cancer meeting at least one of the applicable criteria for the cancer typeas per the medical record and/or clinician referral:

• Breast cancer criteria:

• any diagnosis age 65 or younger;

• diagnosis of triple negative breast cancer at any age;

• multiple primary breast cancers at any age;

• under consideration for PARP therapy;

• any family history (1st, 2nd, or 3rd degree relatives) of ovarian or pancreascancer, or 1 relative with breast cancer who meets the above criteria, or 2relatives with breast cancer at any age; or clinician discretion)

• Colorectal cancer criteria:

• any diagnosis age 50 and below;

• mismatch repair deficient colorectal cancer;

• colorectal cancer at any age with an additional Lynch syndromerelated primarycancer at any age;

• colorectal cancer at any age with a 1st or 2nd degree relative with colorectalcancer at/before age 50;

• colorectal cancer at any age with 2 or more 1st or 2nd degree relatives with aLynch syndrome-related cancer at any age

• Ovarian cancer criteria:

° invasive ovarian cancer

• Pancreatic cancer criteria:

° pancreatic adenocarcinoma

• Prostate cancer criteria:

• castrate-resistant, metastatic prostate cancer;

• high-risk prostate cancer (pending pathology definition)

• Fluency in English, Haitian Creole, or Spanish as per self-report. Fluency isdefined as an answer of "well" or "very well" on the screening questions for spokenability

• No prior cancer genetic counseling or germline testing for cancer risk as perself-report clinician's note, and/or no clinical documentation

Exclusion Criteria:

Phase 1:

• Individuals of impaired decision-making capacity as per a clinician's or consentingprofessional's judgment.

• Subjects who indicate level of fluency as "not at all" or "not well".

Phase 2:

• Individuals of impaired decision-making capacity as per a clinician's or consentingprofessional's judgment.

• Subjects who indicate level of fluency as "not at all" or "not well".