The Engaging Primary Care in Cancer Survivorship (EPICS) Study

Last updated: April 29, 2025
Sponsor: Kaiser Permanente
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Breast Cancer

Cancer

Rectal Cancer

Treatment

Embedded primary care in cancer survivorship model

Clinical Study ID

NCT04745754
R01CA249419
1R01CA249419-01
  • Ages > 21
  • All Genders

Study Summary

A quasi-experimental non-randomized pre/post with control group trial of two models of cancer survivorship care in early-stage colorectal and breast cancer survivors cared for in a community-based, integrated health care setting.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients: Adult (21+) Kaiser Permanente Southern California members diagnosed andtreated for pathologically confirmed first primary early-stage breast (stage 0, I,II) or colorectal (stage I, II) cancer within Kaiser Permanente Southern California.Completed active cancer treatment within the past 6-36 months; active treatmentincludes cancer-directed surgery, chemotherapy (includes Herceptin (Trastuzumab)),radiation therapy, and ovarian suppression therapy (e.g., Goserelin (Zoladex)).Completed at least one office visit within Kaiser Permanente Southern Californiamedical oncology. At low-risk for cancer recurrence and treatment-related toxicitiesbased on state of disease and treatment modalities. For our Aim 2 survey: Primarylanguage of English or Spanish (although we will assess our Aim 1 participants forrecorded preferred spoken language and adjust translations as needed). Ability tocomplete surveys of patient-reported outcomes.

  • Physicians: For centers assigned to the embedded primary care physician (PCP) model,PCPs selected to participate must be Board Certified in a relevant primary carespecialty; hold a valid and current MD or advanced practitioner license; and beemployed by the Southern California Permanente Medical Group.

Exclusion

Exclusion criteria:

  • Patients less than 21 years of age

  • Patients at high risk for recurrence and treatment-related toxicities based on stageof disease and treatment modalities

Study Design

Total Participants: 2450
Treatment Group(s): 1
Primary Treatment: Embedded primary care in cancer survivorship model
Phase:
Study Start date:
September 21, 2021
Estimated Completion Date:
September 30, 2025

Study Description

A quasi-experimental non-randomized pre/post with control group trial of two models of cancer survivorship care in early-stage colorectal and breast cancer survivors cared for in a community-based, integrated health care setting. The trial will test the efficacy of an embedded primary care provider (PCP) model (experimental condition) in which PCPs are embedded within an oncology practice and will care for low-risk survivors who will be transitioned at 6-36 months post-treatment for comprehensive survivorship care. We hypothesize that a) patients in the PCP model will have superior receipt of recommended care compared to usual care; b) patients in the PCP model will perceive significantly better care coordination, self-efficacy, and confidence in their PCP compared to usual care; and c) use of unplanned and non-recommended care will be less in the PCP model compared to usual care.

Connect with a study center

  • Kaiser Permanente Orange County Anaheim/Irvine Medical Center Oncology Clinics

    Anaheim, California 92806
    United States

    Site Not Available

  • Kaiser Permanente Baldwin Park Medical Center Oncology Clinic

    Baldwin Park, California 91706
    United States

    Site Not Available

  • Kaiser Permanente Downey/Bellflower Medical Center Oncology Clinics

    Downey, California 90242
    United States

    Site Not Available

  • Kaiser Permanente Fontana Medical Center Oncology Clinic

    Fontana, California 92335
    United States

    Site Not Available

  • Kaiser Permanente South Bay Medical Center Oncology Clinic

    Harbor City, California 90710
    United States

    Site Not Available

  • Kaiser Permanente Kern County Medical Facilities Oncology Clinic

    Kern, California 93306
    United States

    Site Not Available

  • Kaiser Permanente Antelope Valley Medical Center Oncology Clinic

    Lancaster, California 93534
    United States

    Site Not Available

  • Kaiser Permanente Los Angeles Medical Center Oncology Clinic

    Los Angeles, California 90027
    United States

    Site Not Available

  • Kaiser Permanente West Lost Angeles Medical Center Oncology Clinic

    Los Angeles, California 90034
    United States

    Site Not Available

  • Kaiser Permanente Panorama City Medical Center Oncology Clinic

    Panorama City, California 91402
    United States

    Site Not Available

  • Kaiser Permanente Riverside/Palm Springs Medical Center Oncology Clinics

    Riverside, California 92505
    United States

    Site Not Available

  • Kaiser Permanente San Diego Medical Center Oncology Clinics

    San Diego, California 92123
    United States

    Site Not Available

  • Kaiser Permanente Woodland Hills Medical Center Oncology Clinic

    Woodland Hills, California 91367
    United States

    Site Not Available

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