The Impact of Food Order on Glycemic Excursions in Type 2 Diabetes Assessed by Continuous Glucose Monitoring

Last updated: October 27, 2023
Sponsor: Weill Medical College of Cornell University
Overall Status: Completed

Phase

N/A

Condition

Diabetes And Hypertension

Diabetes Prevention

Diabetes Mellitus, Type 2

Treatment

Carbohydrate-First Meal Sequence

Carbohydrate-Last Meal Sequence

Clinical Study ID

NCT04738799
20-03021613
  • Ages > 21
  • All Genders

Study Summary

The purpose of this study is to explain the effect of food order/nutrient sequencing on glycemic excursions over a 2 week period, utilizing a device known as a continuous glucose monitor (CGM), for people who have been diagnosed with Type 2 Diabetes Mellitus and treated with metformin. This research study is being done because recent studies demonstrate that besides carbohydrate amount and type, the sequential order of macronutrient consumption during a meal has a significant impact on post-meal glucose levels.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Metformin-treated type 2 diabetes of less than 10 years duration
  • Must be on a stable dose of metformin for at least 1 month
  • HbA1c ≤8.5 percent

Exclusion

Exclusion Criteria:

  • Relevant food allergies
  • Oral steroid therapy within 90 days of enrollment
  • Anti-diabetic medications other than metformin
  • History of bariatric surgery
  • Pregnant women
  • Any participant deemed unsuitable in the investigator's opinion

Study Design

Total Participants: 20
Treatment Group(s): 2
Primary Treatment: Carbohydrate-First Meal Sequence
Phase:
Study Start date:
April 29, 2021
Estimated Completion Date:
July 03, 2023

Connect with a study center

  • Weill Cornell Medicine

    New York, New York 10021
    United States

    Site Not Available

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