Efficacy of Intense Pulsed Light in the Treatment of Facial Telangiectasia in Systemic Lupus Erythematosus

Last updated: May 15, 2021
Sponsor: Second Xiangya Hospital of Central South University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cutaneous Lupus Erythematosus

Lupus

Systemic Lupus Erythematosus

Treatment

N/A

Clinical Study ID

NCT04717583
SecondXHCSU-PFK2020SLE01
  • Ages 18-65
  • All Genders

Study Summary

This clinical trial intends to evaluate the efficacy and safety of intense pulsed light (IPL) in the treatment of facial telangiectasia in patients with systemic lupus erythematosus (SLE).

Eligibility Criteria

Inclusion

Inclusion Criteria:

    1. Age: between 18 and 65 years; 2. Patients definitedly diagnosed with systemic lupuserythematosus according to "Diagnostic Criteria for systemic lupus erythematosus"; 3.Patients receiving continuous treatment of glucocorticoid in the last 4 weeks.

Exclusion

Exclusion Criteria:

    1. Patients with severe diseases of heart, brain, lungs, liver, kidney, or bloodsystem; 2. Patients with drug abuse, alcohol abuse, or mental disorders that areunable to cooperate or adhere to treatment; 3. Pregnant women, lactating women orwomen who are ready to conceive within 6 months; 4. Participated in other clinicaltrials within 3 months before the screening.

Study Design

Total Participants: 20
Study Start date:
February 01, 2021
Estimated Completion Date:
December 31, 2022

Study Description

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can involve multiple organs and systems. The treatment for SLE mainly depends on long-term use of glucocorticoids. For many patients with SLE, facial telangiectasia is a commonly seen side effect of long-term use of glucocorticoids. Featured by facial erythema with or without flushing or burning sensation, facial telangiectasia seriously affects the quality of life of patients. However, up to now, there has been little attention paid to this condition in SLE patients. There have been a lack of effective treatment options for tackling this problem.

Intense pulsed light (IPL) is a non-laser light source used to treat a variety of vascular and pigmented lesions. Unlike ultraviolet that is harmful to patients with SLE, application of IPL may be a safe and effective treatment for SLE patients with facial telangiectasia. This study intends to evaluate the efficacy and safety of IPL in the treatment of facial telangiectasia for SLE patients that has been treated with long-term corticosteroids.

Connect with a study center

  • The Second Xiangya Hospital of Central South University

    Changsha, Human 410011
    China

    Active - Recruiting

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