Sentinel Lymph Node Assessment in Ovarian Cancer (TRSGO-SLN-OO5)

Last updated: February 9, 2021
Sponsor: Acibadem University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Vaginal Cancer

Ovarian Cysts

Ovarian Cancer

Treatment

N/A

Clinical Study ID

NCT04714931
TRSGO-SLN-OO5
  • Ages > 18
  • Female

Study Summary

The aim of the study to evaluate the feasibility and accuracy of sentinel lymph node technique in ovarian cancer.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients with Early stage ovarian cancer

Exclusion

Exclusion Criteria:

  • Patient who had been administrated chemotherapy prior to surgery
  • Patients who had diagnosed with malignancy other than ovarian cancer.
  • Patients who had undergone pelvic or paraaortic lymphadenectomy or surgery prior tosurgery.
  • Patients who have allergy for the tracers.

Study Design

Total Participants: 200
Study Start date:
January 01, 2021
Estimated Completion Date:
April 01, 2022

Study Description

Systematic pelvic and paraaortic lymphadenectomy is commonly performed in ovarian cancer patients. However, in early ovarian cancer systematic lymphadenectomy can be an unnecessary procedure which can cause perioperative morbidity and mortality. In the other hand, initially diagnosed early stage ovarian cancer can be upstaged after staging surgery with systematic lymphadenectomy. For preventing unnecessary lymphadenectomy in early ovarian cancer, sentinel lymph node procedure may be an alternative which can prevent major complications without missing the real stage of the disease.

Aim of our study is to assess the feasibility and accuracy of lymph node evaluation with sentinel lymph node technique in early ovarian cancer patients. Pelvic and paraaortic spaces will be evaluated for the sentinel lymph nodes after the injection of the tracers in infundibulopelvic and utero-ovarian ligaments. Than routine systematic pelvic and paraaortic lymphadenectomy will be performed with the routine practice.

Connect with a study center

  • Acibadem MAA University Maslak Hospital

    Istanbul, 34457
    Turkey

    Active - Recruiting

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