Phase
Condition
Allergy
Nasal Obstruction
Eye Disorders/infections
Treatment
N/AClinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Key Inclusion Criteria
- Documented or participant-reported history of birch pollen-triggered allergic rhinitissymptoms, with or without conjunctivitis, for at least 2 years
- Positive Skin prick test (SPT) with birch pollen extract in the screening period, asdefined in the protocol
- Positive Allergen-specific IgE (sIgE) tests for birch pollen and Bet v 1 in thescreening period, as defined in the protocol
- Willing and able to comply with clinic visits and study-related procedures
Exclusion
Key Exclusion Criteria:
- Participation in a prior REGN5713-5714-5715 clinical trial
- Recurrent or chronic rhinitis or sinusitis not associated with birch pollen season, ordue to daily contact with other allergens causing symptoms that are expected tocoincide with birch pollen season, as assessed by the investigator
- Participants who anticipate major changes in allergen exposure in their home or workenvironments that are expected to coincide with the study assessments as assessed bythe investigator
- Persistent chronic or recurring acute infection requiring treatment with antibiotics,antivirals, or antifungals, or any untreated respiratory infections (at the discretionof the investigator) within 4 weeks prior to screening visit. Participants may bere-evaluated for eligibility after symptoms resolve
- Documentation of active SARS-CoV-2 infection, as defined in the protocol
- A clinical history of asthma with 2 or more asthma exacerbations requiringhospitalizations or systemic corticosteroids in the previous year
- History of birch allergy immunotherapy as defined in the protocol
- Use of anti-IgE or other biological therapy in treatment of asthma or allergy within 6months prior to screening NOTE: Other protocol defined Inclusion/Exclusion Criteria apply
Study Design
Connect with a study center
Regeneron Study Site
Gent, Oost-Vlaanderen 9000
BelgiumSite Not Available
Regeneron Study Site
Leuven, Vlaams Brabant 3000
BelgiumSite Not Available
Regeneron Study Site
Kingston, Ontario K7L 2V7
CanadaSite Not Available
Regeneron Study Site
London, Ontario N5W 6A2
CanadaSite Not Available
Regeneron Study Site
Ottawa, Ontario K1G 6C6
CanadaSite Not Available
Regeneron Study Site
Toronto, Ontario M5B 1W8
CanadaSite Not Available
Regeneron Study Site
Trois-Rivieres, Quebec G8T 7A1
CanadaSite Not Available
Regeneron Study Site
Quebec, G1V 4M6
CanadaSite Not Available
Regeneron Study Site
Hvidovre, Capital 2650
DenmarkSite Not Available
Regeneron Study Site
Hellerup, Copenhagen Surroundings 2900
DenmarkSite Not Available
Regeneron Study Site
Vejle, South Jutland 7100
DenmarkSite Not Available
Regeneron Study Site
Heidelberg, Baden-Wurttemberg 69120
GermanySite Not Available
Regeneron Study Site
Stuttgart, Baden-Wurttemberg 70374
GermanySite Not Available
Regeneron Study Site
Dreieich, Hessen 63303
GermanySite Not Available
Regeneron Study Site
Wiesbaden, Hessen 65183
GermanySite Not Available
Regeneron Study Site
Duisburg, Nordrhein-Westfalen 47051
GermanySite Not Available
Regeneron Study Site
Dusseldorf, North Rhine-Westphalia 40225
GermanySite Not Available
Regeneron Study Site
Dresden, Sachsen 01139
GermanySite Not Available
Regeneron Study Site
Berlin, 10117
GermanySite Not Available
Regeneron Study Site
Hamburg, 22549
GermanySite Not Available
Regeneron Study Site
Bangor, Maine 04401
United StatesSite Not Available
Regeneron Study Site
Baltimore, Maryland 21224
United StatesSite Not Available
Regeneron Study Site
Plymouth, Minnesota 55441
United StatesSite Not Available
Regeneron Study Site
Columbia, Missouri 65212
United StatesSite Not Available
Regeneron Study Site
Saint Louis, Missouri 63141
United StatesSite Not Available
Regeneron Study Site
Missoula, Montana 59808
United StatesSite Not Available
Regeneron Study Site
Verona, New Jersey 07044
United StatesSite Not Available
Regeneron Study Site
Great Neck, New York 11021
United StatesSite Not Available
Regeneron Study Site
Cincinnati, Ohio 45231
United StatesSite Not Available
Regeneron Study Site
Toledo, Ohio 43617
United StatesSite Not Available
Regeneron Study Site
Portland, Oregon 97202
United StatesSite Not Available
Regeneron Study Site
Pittsburgh, Pennsylvania 15241
United StatesSite Not Available
Regeneron Study Site
Lincoln, Rhode Island 02865
United StatesSite Not Available
Regeneron Study Site
Greenfield, Wisconsin 53228
United StatesSite Not Available
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