Long-term Sequelae of Childhood Meningitis and Meningococcal Purpura Fulminans

Last updated: March 27, 2024
Sponsor: Centre Hospitalier Intercommunal Creteil
Overall Status: Active - Recruiting

Phase

N/A

Condition

Meningococcal Infection

Meningitis

Treatment

sequela evaluation

Clinical Study ID

NCT04685850
SEINE
  • Ages < 17
  • All Genders

Study Summary

While the initial evolution of meningococcal meningitis (MM) is well described, there are few data on the long-term evolution, beyond 1 year.

The objective of this research is to evaluate the sequelae of MM beyond 1 year in patients with a history of MM followed in Paris area, France. Most children with MM in France have been included in the MM register and are still being followed. Parents will be offered a detailed clinical evaluation of their child including: a clinical and neurological examination, a cognitive performance assessment, an auditory, speech and visual assessment and an evaluation of the child's progress at school.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Infants and children from 0 to 17 years old
  • Having had meningitis or meningococcal purpura fulminans between 2010 and 2021
  • Delay ≥ 1 year between the date of diagnosis of meningitis or purpura meningococcalfulminans and the date of inclusion in the study (signature of the informed consent)
  • The holders of parental authority have read and understood the information letter andtheir express consent has been obtained
  • Patient affiliated to a social security system (Social Security or Universal MedicalCoverage)

Exclusion

Exclusion Criteria:

  • refusal to participate

Study Design

Total Participants: 100
Treatment Group(s): 1
Primary Treatment: sequela evaluation
Phase:
Study Start date:
July 09, 2021
Estimated Completion Date:
July 09, 2026

Connect with a study center

  • CHU Bicêtre

    Le Kremlin Bicêtre, Kremlin Bicêtre 94720
    France

    Site Not Available

  • CHU Annecy

    Annecy, 74370
    France

    Site Not Available

  • CH Argenteuil

    Argenteuil, 95107
    France

    Site Not Available

  • CHU paris Sud site Antoine Béclère

    Clamart, 92140
    France

    Site Not Available

  • Centre Intercommunal de Villeneuve Saint Georges

    Crosne, 91560
    France

    Active - Recruiting

  • CHI créteil

    Créteil, 94000
    France

    Active - Recruiting

  • Groupe Hospitalier Nord Essonne

    Longjumeau, 91345
    France

    Site Not Available

  • CH F Quesnay

    Mantes-la-Jolie, 78200
    France

    Site Not Available

  • GHEF site de Meaux

    Meaux, 77100
    France

    Site Not Available

  • Hôpital Necker Enfants Malades

    Paris, 75015
    France

    Active - Recruiting

  • Robert debré hospital

    Paris, 75019
    France

    Active - Recruiting

  • Ch Pontoise

    Pontoise, 95300
    France

    Site Not Available

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