Feasibility of the Implementation of Tools for Heart Failure Risk Prediction

Last updated: March 18, 2024
Sponsor: Northwestern University
Overall Status: Completed

Phase

N/A

Condition

Chest Pain

Heart Failure

Congestive Heart Failure

Treatment

Heart Failure Prevention Clinic

Clinical Study ID

NCT04684264
STU00210780
  • Ages 30-79
  • All Genders

Study Summary

The purpose of this study is to gather information to develop a heart failure screening and prevention program.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 10-year risk of heart failure >5% based on the PCP-HF equations
  • At least one primary care visit in the last 12 months
  • At least one additional primary care visit in the last 5 years
  • Had cholesterol and glucose checked within the past 5 years

Exclusion

Exclusion Criteria:

  • History of cardiovascular disease
  • Signs and symptoms of heart failure
  • Estimated glomerular filtration rate <45 mL/min/1.73m^2
  • Stage 3 or 4 cancer
  • Pregnancy

Study Design

Total Participants: 101
Treatment Group(s): 1
Primary Treatment: Heart Failure Prevention Clinic
Phase:
Study Start date:
March 03, 2021
Estimated Completion Date:
February 01, 2024

Study Description

All participants will undergo phlebotomy for specimen collection (BNP, hs-cTn, BMP and lipid testing, biorepository storage) and baseline echocardiography. All participants will additionally be administered a health and lifestyle questionnaire, undergo measurement of vital signs, and receive uniform education on heart-healthy lifestyle and signs and symptoms of heart failure. Participants who are randomized to the intervention arm will receive a referral to Heart Failure Prevention Clinic, a pharmacist-directed practice in collaboration with an attending cardiologist, where they will be followed for 1 year, with their primary care physician updated after each visit. The information from their BNP, hs-cTn, and echocardiography will be provided to them and their primary care physicians as well as the pharmacist and cardiologist team members. The participants (and their primary care providers) who are randomized to usual care will be blinded to their BNP and hs-cTn values and echocardiography results.

Connect with a study center

  • Northwestern University Department of Preventive Medicine

    Chicago, Illinois 60611
    United States

    Site Not Available

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