Cardiogenic Shock Working Group Registry

Last updated: February 21, 2024
Sponsor: Tufts Medical Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Circulation Disorders

Occlusions

Heart Failure

Treatment

Acute Mechanical Circulatory Support Devices

Inotrope

Vasopressor

Clinical Study ID

NCT04682483
12670
  • Ages > 18
  • All Genders

Study Summary

The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients must have cardiogenic shock.

Cardiogenic shock is defined by at least one of the two categories below:

  1. At least 2 of the following concurrently at any point during the index hospitalization:

  • Cardiac Index < 2.2

  • PAPI < 1.0

  • Cardiac Power Output ≤ 0.6

  • MAP < 60mmHg or a >30mmHg drop in MAP from baseline

  • SBP < 90mmHg or a >30mmHg drop in SBP from baseline

  • Pulse > 100

  1. Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target.

Post-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in this registry.

Study Design

Total Participants: 5000
Treatment Group(s): 3
Primary Treatment: Acute Mechanical Circulatory Support Devices
Phase:
Study Start date:
December 04, 2017
Estimated Completion Date:
June 01, 2025

Study Description

The Cardiogenic Shock Working Group is an Academic Research Consortium involving multiple medical centers within the United States and includes a multicenter registry for patients with cardiogenic shock. De-identified clinical variables are collected from medical records and follow-up phone calls. There is currently no central database for cardiogenic shock, therefore analysis of cardiogenic shock on a larger scale is limited. A goal of the Cardiogenic Shock Working Group is to create a centralized registry, compiled of data from multiple institutions, to analyze clinical outcomes. The Cardiogenic Shock Working Group Registry will include a retrospective arm, where data is collected during the course of the hospital stay, and a prospective arm, where long-term outcomes will be assessed.

Connect with a study center

  • Cleveland Clinic Florida

    Weston, Florida 33331
    United States

    Active - Recruiting

  • Northwestern Medicine

    Chicago, Illinois 60611
    United States

    Active - Recruiting

  • University of Chicago

    Chicago, Illinois 60612
    United States

    Active - Recruiting

  • Maine Medical Center

    Portland, Maine 04102
    United States

    Active - Recruiting

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts 02215
    United States

    Active - Recruiting

  • Tufts Medical Center

    Boston, Massachusetts 02111
    United States

    Active - Recruiting

  • Hackensack Meridian Health

    Hackensack, New Jersey 07601
    United States

    Active - Recruiting

  • Columbia University Irving Medical Center

    New York, New York 10032
    United States

    Active - Recruiting

  • Providence St. Vincent Heart Clinic

    Portland, Oregon 97225
    United States

    Active - Recruiting

  • Allegheny General Hospital

    Pittsburgh, Pennsylvania 15212
    United States

    Active - Recruiting

  • University Of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania 15261
    United States

    Active - Recruiting

  • Baylor Scott & White Advanced Heart Failure Clinic

    Dallas, Texas 75201
    United States

    Active - Recruiting

  • University of Texas Medical Branch

    Galveston, Texas 77555
    United States

    Active - Recruiting

  • Houston Methodist Hospital

    Houston, Texas 77030
    United States

    Active - Recruiting

  • Inova Health System

    Falls Church, Virginia 22042
    United States

    Active - Recruiting

  • University of Washington Medical Center

    Seattle, Washington 98195-9472
    United States

    Active - Recruiting

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