Function Integrity of Neck Anatomy in Thyroid Surgery

Last updated: December 11, 2020
Sponsor: Wuhan University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Thyroid Disease

Treatment

N/A

Clinical Study ID

NCT04666103
lycf202007
  • Ages 18-75
  • All Genders

Study Summary

Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment.

Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients diagnosed with unilateral thyroid carcinoma and contralateral benign noduleconfirmed by preoperative ultrasound-guided fine-needle aspiration cytology;
  • Patients with contralateral nodules ≤ 20mm and located in the thyroid gland;
  • Patients with clinical node-negative cervical compartment at palpation and neckultrasound.

Exclusion

Exclusion Criteria:

  • Previous history of neck surgery
  • Previous history of neck radiation therapy

Study Design

Total Participants: 1264
Study Start date:
December 11, 2020
Estimated Completion Date:
December 12, 2026

Connect with a study center

  • Zhongnan Hospital of Wuhan University

    Wuhan, Hubei 430071
    China

    Active - Recruiting

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