COVID-19 Stroke Apical Lung Examination Study

Last updated: May 26, 2021
Sponsor: King's College Hospital NHS Trust
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cerebral Ischemia

Stroke

Treatment

N/A

Clinical Study ID

NCT04640428
COVID SALES 2
  • Ages > 18
  • All Genders

Study Summary

Multi-centre prospective study evaluating computed tomography angiography studies performed for stroke patients as a diagnostic and prognostic imaging biomarker.

Eligibility Criteria

Inclusion

Inclusion Criteria: All adult patients presenting with clinical features of acute ischaemic stroke undergoinginvestigation with computed tomography angiography at presentation.

Exclusion

Exclusion Criteria: Poor image quality. No radiologist report available. Computed tomography angiographyperformed in a non-acute setting.

Study Design

Total Participants: 2000
Study Start date:
July 10, 2020
Estimated Completion Date:
October 31, 2021

Study Description

Diagnosis of coronavirus disease 2019 (COVID-19) relies on clinical features and reverse-transcriptase polymerase chain reaction (RT-PCR) testing. The latter is constrained by limited sensitivity and a timescale of hours to yield results, with no point-of-care test widely available. A dedicated computed tomography study of the chest is likely to be more sensitive than RT-PCR for COVID-19. Carotid computed tomography angiography (CTA) is a routine acute stroke investigation and includes the lung apices. We aim to assess the lung apices on CTA for ground glass opacification and compare this with COVID-19 RT-PCR test results and clinical outcome measures.

Connect with a study center

  • Royal United Hospitals Bath NHS Foundation Trust

    Bath,
    United Kingdom

    Active - Recruiting

  • North Bristol NHS Trust

    Bristol,
    United Kingdom

    Active - Recruiting

  • University Hospitals Bristol NHS Foundation Trust

    Bristol,
    United Kingdom

    Active - Recruiting

  • Frimley Health NHS Foundation Trust

    Camberley,
    United Kingdom

    Active - Recruiting

  • Addenbrooke's University Hospital NHS Foundation Trust

    Cambridge, CB2 0QQ
    United Kingdom

    Site Not Available

  • Cardiff and Vale University Health Board

    Cardiff,
    United Kingdom

    Active - Recruiting

  • University Hospitals Coventry and Warwickshire NHS Trust

    Coventry,
    United Kingdom

    Active - Recruiting

  • Royal Devon and Exeter NHS Foundation Trust

    Exeter,
    United Kingdom

    Site Not Available

  • Leeds Teaching Hospitals NHS Trust

    Leeds,
    United Kingdom

    Active - Recruiting

  • Guy's and St Thomas' NHS Foundation Trust

    London,
    United Kingdom

    Active - Recruiting

  • Imperial College Healthcare NHS Foundation Trust

    London,
    United Kingdom

    Active - Recruiting

  • King's College Hospital NHS FT (KCH)

    London,
    United Kingdom

    Active - Recruiting

  • King's College Hospital NHS FT (PRUH)

    London,
    United Kingdom

    Active - Recruiting

  • University College London NHS Foundation Trust

    London,
    United Kingdom

    Active - Recruiting

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