Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Critically Ill Patients

Last updated: November 28, 2023
Sponsor: University Hospital, Geneva
Overall Status: Completed

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT04624009
SjvO2 vs ScvO2 / HUG-DMA
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

ScvO2 is an important parameter in the management of critically ill patient. The only way to measure it is to have an internal jugular or subclavian central venous catheter. With this trial, the investigators want to show a positive relationship between invasive ScvO2 measurement and noninvasive SjvO2 measurement with VO 100 medical device from Mespere LifeSciences, allowing the use of SjvO2 as a noninvasive surrogate of ScvO2 in critically ill patients.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • all ICU adult patients routinely equipped with a central venous catheter placed ininternal jugular or subclavian vein allowing ScvO2 measurement from blood sampling. The investigators will perform this study only on patients already equipped with aninternal jugular CVC. In other words, the placement of the CVC is not conditioned by thestudy realization.

Exclusion

Exclusion Criteria:

  • patients with CVC placed in another site than internal jugular vein.

Study Design

Total Participants: 35
Study Start date:
January 01, 2022
Estimated Completion Date:
August 01, 2023

Study Description

ScvO2 measures central venous oxygen saturation level from veins draining the head and upper body while SvO2 measures mixed venous oxygen saturation from the lower and upper half of the body. ScvO2 is more conveniently measured and less risky than Sv02 measurement although a central venous catheter is needed. ScvO2 gives knowledge about the balance between the delivery of oxygen and oxygen consumption in the body. Interest in ScvO2 monitoring in anesthesia and critical care has been debated. However, ScvO2 is still recommended as a major hemodynamic target of early resuscitation of critically ill patients. Even if ScvO2 measurement is far less invasive than SvO2 measurement through pulmonary artery catheter, it is accompanied with morbidity.

VO 100 medical device from Mespere LifeSciences allows a non-invasive measurement of SjvO2 using the NIRS technique. Jugular venous oxygen saturation (SjvO2) is a measurement of the amount of oxygen left in the venous system after the brain has removed the oxygen that it needs.

On the same principle that a positive relationship between ScvO2 and SvO2 has been shown, what the investigators are trying to do is to show a positive relationship between SjvO2 and ScvO2 in order to possibly use in the future SjvO2 measured by VO 100 as a noninvasive surrogate of ScvO2.

Connect with a study center

  • University of Geneva

    Geneva, 1211
    Switzerland

    Site Not Available

  • Eduardo Schiffer

    Veyrier, 1255
    Switzerland

    Site Not Available

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