Operating Room Air Filtration/Sterilization

Last updated: January 8, 2025
Sponsor: The Cleveland Clinic
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Surgery

Treatment

Functioning Aerus air filtration/sterilization

Deactivated Aerus air filtration/sterilization

Clinical Study ID

NCT04610294
20-656
  • Ages > 18
  • All Genders

Study Summary

Determine whether operating room air filtration and sterilization with the ActivePure system reduces a composite of serious surgical site infections, infection-related complications, and death within 30 days after surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • All patients in designated adult operating rooms

  • American Society of Anesthesiologists physical status 1-4.

  • Surgery lasting at least 1 hour.

Study Design

Total Participants: 66273
Treatment Group(s): 2
Primary Treatment: Functioning Aerus air filtration/sterilization
Phase:
Study Start date:
May 01, 2021
Estimated Completion Date:
December 31, 2025

Study Description

The investigators primary goal is thus to determine whether supplemental filtering and sterilizing operating room air reduces a composite of serious surgical site infections, infection-related complications, and death within 30 days after surgery. The primary outcome will be restricted to inpatients. However, outpatients will be simultaneously enrolled given the trial's cluster design. Sample-size is based on our primary inpatient analysis, N= 66,273 inpatients. Available outpatients will be included for analysis of our secondary outcome which includes both inpatients and outpatients.

Connect with a study center

  • Cleveland Clinic

    Cleveland, Ohio 44195
    United States

    Site Not Available

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