Postoperative Pain Management of Therapeutic Surgery: a Prospective, Observational Cohort Study.

Last updated: September 22, 2025
Sponsor: China Medical University Hospital
Overall Status: Completed

Phase

N/A

Condition

Pain

Post-surgical Pain

Chronic Pain

Treatment

ERDS group

Clinical Study ID

NCT04578483
CMUH109-REC3-101
  • Ages 20-80
  • All Genders

Study Summary

Poor management of post-operative acute pain can contribute to medical complications including pneumonia, deep vein thrombosis, infection and delayed healing, as well as the development of chronic. In contrast, appropriate pain control is capable of reducing the postoperative complications, preventing the development of chronic pain, and improving the quality of life. The workloads of medical staffs and health care cost are subsequently decreased. Recently, a lot of analgesic methods have been developed and used in clinical practice, such as patient-controlled analgesia, ultrasound-guided long-term analgesia and multimodal analgesia. This study is aimed to investigate the effect of dinalbuphine sebacate, a long-acting analgesic, in postoperative pain management. This real world data can serve as a reference toward high health care quality.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Aged 20 to 80.

  2. Needing pain management after elective surgery.

  3. American Society of Anesthesiology Physical Class (ASA) between 1 and 3.

Exclusion

Exclusion Criteria:

  1. Allergic to anesthetics, opioids, or medicine used during study period.

  2. Severe comorbidity, such as cardiopulmonary disease and strock.

  3. Abuse or long-term use of opioids.

  4. Pregnant or breastfeeding.

  5. Judged to be unsuitable subjects by investigator.

Study Design

Total Participants: 634
Treatment Group(s): 1
Primary Treatment: ERDS group
Phase:
Study Start date:
October 27, 2020
Estimated Completion Date:
December 31, 2022

Study Description

This is a prospective, observational, cohort study. Patients undergoing elective surgery will be invited to the study. The written informed consent will be obtained prior to participation. Demographic data, underlying condition, surgical procedures, consumption of anesthetics and analgesics, analgesic methods, postoperative complications, pain intensity and life quality will be collected from medical history and by questionnaires.

Connect with a study center

  • China Medical University Hsinchu Hospital

    Hsinchu, 302
    Taiwan

    Site Not Available

  • China Medical University Hsinchu Hospital

    Hsinchu 1675151, 302
    Taiwan

    Site Not Available

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