Scleral Lens Fitting Using Wide-Field OCT

Last updated: September 5, 2025
Sponsor: Oregon Health and Science University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Vision Loss

Eye Disease

Treatment

N/A

Clinical Study ID

NCT04570020
6612-SCLERAL LENS
R01EY028755
  • Ages > 18
  • All Genders

Study Summary

The purpose of this study is to see if OCT technology can optimize scleral contact lens fittings. Subjects with keratoconus, post-penetrating keratoplasty (PK), post-LASIK ectasia, post-radial keratotomy (RK), or a variety of anterior surface disorders requiring scleral lens fittings will be considered for enrollment. For each study eye, a clinically-selected scleral lens fit will be compared against an OCT-selected lens fit. The quality of each lens fit will be determined by flourescein exam at the slit lamp. Apical clearance, limbal clearance, conjunctival compression, and lens edge lift will be assessed. A lens that satisfies all four criteria will be considered satisfactory.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Eyes requiring fit for scleral lenses for KCN, post-PK, post-RK, post-LASIK ectasia,or various anterior surface disorders

Exclusion

Exclusion Criteria:

  • Inability to maintain stable fixation for OCT imaging

  • Inability to commit to required visits to complete the study

  • Eyes with concurrent retinal diseases, glaucoma, or other eye conditions that maylimit visual outcome

Study Design

Total Participants: 258
Study Start date:
September 23, 2020
Estimated Completion Date:
December 31, 2028

Connect with a study center

  • Oregon Health & Science University, Casey Eye Institute

    Portland, Oregon 97239
    United States

    Site Not Available

  • Oregon Health & Science University, Casey Eye Institute

    Portland 5746545, Oregon 5744337 97239
    United States

    Active - Recruiting

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