Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs

Inclusion Criteria:

• A high index of suspicion for discogenic pain, i.e. painful degenerative discs with orwithout protrusions/herniations and facet/sacroiliac joint pain

• Patients with mild to severe spinal stenosis

• Patients with radiculopathy

• Patients with disc extrusions

• Patients with failed spinal fusion

• Patients with mild to severe facet arthropathy

• Patients with suspected sacroiliac joint disease

• Age 18 to 60 years

• Mild to severe loss of intervertebral disc height

• Pain is not responsive to conservative treatment measures (oral medication, epiduralsteroid injections, physical therapy)

• Pain persists for an extended period of time (i.e., at least 3 months)

• High intensity zone (HIZ) in annular fissure or adjacent to annular fissure detectedon T2 or STIR MRI

• No evidence of contraindications to undergo procedure such as pregnancy, activeinfection, bleeding disorder, or metastatic cancer

• English speaking

Exclusion Criteria:

• Spinal Deformity (Scoliosis >20 degrees, Spondylolisthesis)

• Sequestered fragments, severe thecal sac compression

• Severe neurologic deficit

• Non-English speaking

• Bone marrow disorders

• Immunosuppressed Patients

• Patients with coagulopathy

• Localized infection in the area of skin penetration

• Spinal infection

• Serious medical co-morbidities