Description of Characteristics, Such as Age, Previous and Concurrent Treatments, Associated Diseases, of Patients With Asthma Treated With Dupilumab (DUPIXENT)

Last updated: July 29, 2025
Sponsor: Sanofi
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Asthma

Treatment

Dupilumab SAR231893

Clinical Study ID

NCT04550962
OBS16688
  • Ages > 12
  • All Genders

Study Summary

Primary Objective:

The primary objective of the study is to characterize patients initiating DUPIXENT for asthma in a real-world setting, with respect to their medical history, including asthma history and asthma treatment history, socio-demographic, biomarkers (including Fractional exhaled nitric oxide [FeNO]), and concomitant treatments for asthma.

Secondary Objectives:

The secondary objectives of the study are:

  • To characterize real-world use patterns of DUPIXENT for asthma (eg, most commonly used regimens, reason for initiation of new asthma treatments, concomitant therapies, treatment durations, and reasons for discontinuation and/or switching)

  • To assess the effectiveness of DUPIXENT in asthma patients in a real world setting (lung function improvement, exacerbation rate, asthma control)

  • To assess comorbid type 2 conditions (atopic/allergic) and patterns of use and effects of treatment in comorbid conditions in asthma patients treated with Dupixent

  • To collect data on HealthCare Resource Utilization (HCRU)

  • To collect safety data on study participants in the real-world setting.

Eligibility Criteria

Inclusion

  • Male or female, 12 years or older Initiating treatment with Dupixent for asthma according to the country-specific prescribing information Willing and able to comply with the required clinic visits, study procedures and assessments.

Provided signed informed consent

  • Most important exclusion criteria for potential participants Patients who have a contraindication to Dupixent according to the country-specific prescribing information Treatment with Dupixent within 6 months before the baseline visit. Note: for patients who have been treated previously with DUPIXENT a washout period of 6 months is required before Visit 1.

Any condition that, in the opinion of the Investigator, may interfere with patient's ability to participate in the study, such as short life expectancy, substance abuse, severe cognitive impairment, or other comorbidities that can predictably prevent the patient from adequately completing the schedule of visits and assessments Patients currently participating in any interventional clinical trial which modifies patient care.

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Study Design

Total Participants: 376
Treatment Group(s): 1
Primary Treatment: Dupilumab SAR231893
Phase:
Study Start date:
November 02, 2020
Estimated Completion Date:
July 01, 2026

Study Description

Each patient will be followed during 36 months.

Connect with a study center

  • Investigational Site Number :0320001

    Ciudad de Buenos Aires, Buenos Aires
    Argentina

    Site Not Available

  • Investigational Site Number : 0320005

    La Plata, Buenos Aires B1900BNN
    Argentina

    Site Not Available

  • Investigational Site Number :0320005

    La Plata, Buenos Aires B1900BNN
    Argentina

    Site Not Available

  • Investigational Site Number : 0320006

    Villa Rosa, Buenos Aires 1631
    Argentina

    Site Not Available

  • Investigational Site Number :0320006

    Villa Rosa, Buenos Aires 1631
    Argentina

    Site Not Available

  • Investigational Site Number :0320003

    Rosario, Santa Fe S2000BRH
    Argentina

    Site Not Available

  • Investigational Site Number :0320009

    San Miguel de Tucumán, Tucumán T4000IAR
    Argentina

    Site Not Available

  • Investigational Site Number : 0320001

    Ciudad Autonoma Bs As, C1121ABE
    Argentina

    Site Not Available

  • Investigational Site Number :0320001

    Ciudad Autonoma Bs As, C1121ABE
    Argentina

    Site Not Available

  • Investigational Site Number : 0320008

    Ciudad Autonoma Buenos Aires, C1425BEN
    Argentina

    Site Not Available

  • Investigational Site Number :0320008

    Ciudad Autonoma Buenos Aires, C1425BEN
    Argentina

    Site Not Available

  • Investigational Site Number : 0320009

    San Miguel de Tucuman, T4000IAI
    Argentina

    Site Not Available

  • Investigational Site Number :0320009

    San Miguel de Tucuman, T4000IAI
    Argentina

    Site Not Available

  • Investigational Site Number : 0320004

    Santa Fe, 3000
    Argentina

    Site Not Available

  • Investigational Site Number :0320004

    Santa Fe, 3000
    Argentina

    Site Not Available

  • Investigational Site Number : 1520001

    Santiago, Reg Metropolitana De Santiago 7500692
    Chile

    Site Not Available

  • Investigational Site Number :1520001

    Santiago, Reg Metropolitana De Santiago 7500692
    Chile

    Site Not Available

  • Investigational Site Number : 1520002

    Quillota, Valparaíso 2260877
    Chile

    Site Not Available

  • Investigational Site Number :1520002

    Quillota, Valparaíso 2260877
    Chile

    Site Not Available

  • Investigational Site Number : 1700009

    Barranquilla, 080001
    Colombia

    Site Not Available

  • Investigational Site Number :1700009

    Barranquilla, 080001
    Colombia

    Active - Recruiting

  • Investigational Site Number : 1700004

    Bogota,
    Colombia

    Site Not Available

  • Investigational Site Number :1700004

    Bogota,
    Colombia

    Active - Recruiting

  • Investigational Site Number : 1700003

    Bucaramanga,
    Colombia

    Site Not Available

  • Investigational Site Number :1700003

    Bucaramanga,
    Colombia

    Active - Recruiting

  • Investigational Site Number :3000001

    Ioannina, 45500
    Greece

    Site Not Available

  • Investigational Site Number :3000002

    Thessaloniki, 57010
    Greece

    Site Not Available

  • Investigational Site Number : 3760008

    Ashdod, 7747629
    Israel

    Site Not Available

  • Investigational Site Number :3760008

    Ashdod, 7747629
    Israel

    Site Not Available

  • Investigational Site Number : 3760004

    Ashkelon, 78278
    Israel

    Site Not Available

  • Investigational Site Number :3760004

    Ashkelon, 78278
    Israel

    Site Not Available

  • Investigational Site Number : 3760003

    Jerusalem, 91120
    Israel

    Site Not Available

  • Investigational Site Number : 3760005

    Jerusalem, 91031
    Israel

    Site Not Available

  • Investigational Site Number :3760003

    Jerusalem, 91120
    Israel

    Site Not Available

  • Investigational Site Number :3760005

    Jerusalem, 91031
    Israel

    Site Not Available

  • Investigational Site Number : 3760001

    Kfar Saba, 4428164
    Israel

    Site Not Available

  • Investigational Site Number :3760001

    Kfar Saba, 4428164
    Israel

    Active - Recruiting

  • Investigational Site Number :3760002

    Petah-Tikva, 49100
    Israel

    Site Not Available

  • Investigational Site Number : 3760006

    Rehovot, 7642001
    Israel

    Site Not Available

  • Investigational Site Number :3760006

    Rehovot, 7642001
    Israel

    Active - Recruiting

  • Investigational Site Number : 3760007

    Tel Aviv, 64239
    Israel

    Site Not Available

  • Investigational Site Number :3760007

    Tel Aviv, 64239
    Israel

    Active - Recruiting

  • Investigational Site Number : 4140001

    Kuwait, 00000
    Kuwait

    Site Not Available

  • Investigational Site Number :4140001

    Kuwait, 00000
    Kuwait

    Site Not Available

  • Investigational Site Number : 4220003

    Achrafieh,
    Lebanon

    Site Not Available

  • Investigational Site Number :4220003

    Achrafieh,
    Lebanon

    Site Not Available

  • Investigational Site Number : 4220001

    Beirut,
    Lebanon

    Site Not Available

  • Investigational Site Number : 4220002

    Beirut, 11 0236
    Lebanon

    Site Not Available

  • Investigational Site Number :4220001

    Beirut,
    Lebanon

    Site Not Available

  • Investigational Site Number :4220002

    Beirut, 11 0236
    Lebanon

    Active - Recruiting

  • Investigational Site Number :4840001

    Guadalajara, Jalisco 44100
    Mexico

    Site Not Available

  • Investigational Site Number : 4840003

    Durango, 34000
    Mexico

    Site Not Available

  • Investigational Site Number :4840003

    Durango, 34000
    Mexico

    Active - Recruiting

  • Investigational Site Number : 6340001

    Doha,
    Qatar

    Site Not Available

  • Investigational Site Number :6340001

    Doha,
    Qatar

    Active - Recruiting

  • Investigational Site Number : 6430005

    Chelyabinsk, 454091
    Russian Federation

    Site Not Available

  • Investigational Site Number :6430005

    Chelyabinsk, 454091
    Russian Federation

    Site Not Available

  • Investigational Site Number : 6430004

    Moscow, 115522
    Russian Federation

    Site Not Available

  • Investigational Site Number : 6430007

    Moscow, 105077
    Russian Federation

    Site Not Available

  • Investigational Site Number :6430004

    Moscow, 115522
    Russian Federation

    Site Not Available

  • Investigational Site Number :6430007

    Moscow, 105077
    Russian Federation

    Site Not Available

  • Investigational Site Number : 6430006

    Rostov-on-Don, 344012
    Russian Federation

    Site Not Available

  • Investigational Site Number :6430006

    Rostov-on-Don, 344012
    Russian Federation

    Site Not Available

  • Investigational Site Number : 6430008

    Saratov, 410012
    Russian Federation

    Site Not Available

  • Investigational Site Number :6430008

    Saratov, 410012
    Russian Federation

    Site Not Available

  • Investigational Site Number : 6430002

    Stavropol, 355020
    Russian Federation

    Site Not Available

  • Investigational Site Number :6430002

    Stavropol, 355020
    Russian Federation

    Site Not Available

  • Investigational Site Number : 6820005

    Jeddah, 23433
    Saudi Arabia

    Site Not Available

  • Investigational Site Number :6820005

    Jeddah, 23433
    Saudi Arabia

    Active - Recruiting

  • Investigational Site Number :6820008

    Jeddah, 22252
    Saudi Arabia

    Active - Recruiting

  • Investigational Site Number : 6820004

    Makkah, 24246
    Saudi Arabia

    Site Not Available

  • Investigational Site Number :6820004

    Makkah, 24246
    Saudi Arabia

    Active - Recruiting

  • Investigational Site Number : 6820001

    Riyadh, 12713
    Saudi Arabia

    Site Not Available

  • Investigational Site Number : 6820002

    Riyadh, 11525
    Saudi Arabia

    Site Not Available

  • Investigational Site Number :6820001

    Riyadh, 12713
    Saudi Arabia

    Active - Recruiting

  • Investigational Site Number :6820002

    Riyadh, 11525
    Saudi Arabia

    Active - Recruiting

  • Investigational Site Number : 7020001

    Singapore, 169308
    Singapore

    Site Not Available

  • Investigational Site Number : 7020002

    Singapore, 119074
    Singapore

    Site Not Available

  • Investigational Site Number :7020001

    Singapore, 169308
    Singapore

    Site Not Available

  • Investigational Site Number :7020002

    Singapore, 119074
    Singapore

    Site Not Available

  • Investigational Site Number : 7840006

    Abu Dhabi, 0000
    United Arab Emirates

    Site Not Available

  • Investigational Site Number :7840006

    Abu Dhabi, 0000
    United Arab Emirates

    Site Not Available

  • Investigational Site Number : 7840001

    Dubai, 4545
    United Arab Emirates

    Site Not Available

  • Investigational Site Number : 7840007

    Dubai, 2
    United Arab Emirates

    Site Not Available

  • Investigational Site Number :7840001

    Dubai, 4545
    United Arab Emirates

    Site Not Available

  • Investigational Site Number :7840007

    Dubai, 2
    United Arab Emirates

    Site Not Available

  • Investigational Site Number 7840005

    Ras Al Khaimah, 00000
    United Arab Emirates

    Site Not Available

  • Investigational Site Number : 7840002

    Sharjah, 3499
    United Arab Emirates

    Site Not Available

  • Investigational Site Number : 7840004

    Sharjah, 00000
    United Arab Emirates

    Site Not Available

  • Investigational Site Number :7840002

    Sharjah, 3499
    United Arab Emirates

    Completed

  • Investigational Site Number :7840004

    Sharjah, 00000
    United Arab Emirates

    Site Not Available

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