Financial Toxicity and Quality of Life in Patients With TGCT

Last updated: March 17, 2025
Sponsor: The University of Texas Health Science Center at San Antonio
Overall Status: Active - Recruiting

Phase

N/A

Condition

Urologic Cancer

Treatment

EORTC QLQ C-30

Functional Assessment of Cancer Therapy: General (FACT-G)

EORTC QLQ-TC26.

Clinical Study ID

NCT04531709
CTMS 20-0061
HSC20200462E
  • Ages > 18
  • Male

Study Summary

This is a cross-sectional, observational study employing validated questionnaires to investigate financial toxicity in subjects with testicular germ cell tumors (TGCT). As background, TGCTs are the most common malignancies among men from age 15-35. Treatment is highly curative, but often consists of intensive multi-cycle chemotherapy with significant potential for physical toxicity. The treatment course itself is disruptive and long term physical and mental health consequences can increase risk for financial toxicity. Thus, we aim to study financial toxicity in both patients with TGCT actively receiving treatment and in TGCT survivors. There will be two separate cohorts: Cohort 1 will consist of subjects with recently diagnosed TGCT who will undergo multi-agent, multi-cycle chemotherapy and Cohort 2 will consist of subjects who have completed chemotherapy and are long-term survivors.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age > 18 years of age

  • Patients with histologically or clinically confirmed germ cell tumor.

  • Completed treatment for germ cell tumor with multicycle (> 2 cycles) / multiagentchemotherapy.

  • Within years 1-5 of surveillance since Day 1 of last cycle of chemotherapy

  • Signed informed consent

Exclusion

Exclusion Criteria:

  • Long-term survivors

  • Patients undergoing active chemotherapy

  • Patients who did not complete 1st line chemotherapy.

Study Design

Total Participants: 30
Treatment Group(s): 4
Primary Treatment: EORTC QLQ C-30
Phase:
Study Start date:
March 01, 2023
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • Mays Cancer Center

    San Antonio, Texas 78229
    United States

    Active - Recruiting

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