A Study of Sodium Oligomannate (GV-971) in Participants With Mild to Moderate Alzheimer's Disease

Inclusion Criteria:

• Mild to moderate AD per NIA-AA.
• History of cognitive and functional decline over at least 1 year.
• MMSE scores between 11 and 24 (inclusive) at baseline.
• Brain MRI scan show the highest possibility of AD.
• Have a study partner/caregiver.

Exclusion Criteria:

• Diagnosis of a dementia-related central nervous system disease other than AD.
• Major structural brain disease as judged by MRI.
• A resting heart rate of < 50 beats per minute (bpm) after 5 minutes of rest in sittingor supine position.
• Major medical illness or unstable medical condition within 6 months of screening.
• Concomitant use of AChEIs and/or memantine within 30 days before first MMSE score, andduring the study.
• Inadequate hepatic function.
• Inadequate organ and marrow function.
• ECG clinically significant abnormalities.