Diffusion Tensor (DTI) for the Assessement of Therapeutic Evolution of Patients With Acute Lumbar Radiculalgia

Last updated: March 25, 2024
Sponsor: Lille Catholic University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Lower Back Pain

Radiculopathy

Spondylolisthesis

Treatment

DTI sequence acquisition

Clinical Study ID

NCT04507113
RC-P0074
  • Ages > 18
  • All Genders

Study Summary

Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots. DTI is a widely used neuroimaging technique and is a current topic of research in the field of peripheral nerve imaging.The aim of the study is to determine the prognostic quality of the DTI parameters to predict the therapeutic evolution of patients with lumbar radiculalgia at 6 months.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age ≥ 18 ans
  • Patient with Lumbar Radiculalgia (L4, L5 or S1)
  • Pain VAS (Visual analog scale) > 30/100
  • Less than 3 months of evolution
  • With a radiculalgia superior or equal to lumbalgia
  • Disco radicular conflict, verified by MRI
  • Able to receive information
  • Affiliated to French social security

Exclusion

Exclusion Criteria:

  • History of chronic lumbalgia and radiculalgia
  • History of lumbar surgery
  • Recent episode (less than 6 months) with the same radicular topography
  • Bilateral radicular compression on MRI
  • Patient requiring emergency surgery
  • Evolutive disease interfering with pain assesment (neoplasia, inflammatory rheumatism,peripheral neuropathy, central neurological disease)
  • MRI contraindication

Study Design

Total Participants: 150
Treatment Group(s): 1
Primary Treatment: DTI sequence acquisition
Phase:
Study Start date:
April 06, 2022
Estimated Completion Date:
November 06, 2025

Connect with a study center

  • Groupe Hospitalier de l'Institut Catholique de Lille

    Lomme, 59 462
    France

    Active - Recruiting

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