The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

Inclusion Criteria:

• Subject Age is > 18

• Subject with a Head CT that demonstrates an acute, spontaneous, primary,supratentorial ICH of volume > 20 mL, assessed via standard of care techniques

• Subject Surgery can be initiated within 24 hours of the last known well time or, inpatients with wake-up onset, within 24 hours of the time the patient awoke withsymptoms.

• Subject has a NIHSS score > 5

• Subject has a baseline Modified Rankin Scale (mRS) Score ≤ 2

• Subject with a CT Angiography demonstrating no vascular malformation

Exclusion Criteria:

• Subject has an underlying vascular lesion defined as causative source of ICH

• Subject has a profound neurological deficit defined as fixed/dilated pupils orbilateral extensor motor posturing

• Subject has an Infratentorial or brainstem ICH

• Subject has a known life expectancy < 6 months

• Subject has an uncorrectable coagulopathy

• Subject has a mechanical heart valve

• Subject is pregnant

• Subject participates in another concurrent interventional clinical trial

• Subject who is unable to meet study follow-up requirements