Qingfei Granule for the Treatment of the Pediatric Acute Upper Respiratory Tract Infection With Bacterial Infection

Inclusion Criteria:

1. Diagnosis with the acute upper respiratory tract infection;
2. Diagnosis with wind-heat Zheng according to Chinese medicine;
3. Age: 5-14 years old;
4. Body temperature ≥ 37.5 ℃;
5. White blood cell count> 12 × 10^9 / L, and / or neutrophil ratio over than 70%;
6. The informed consent process complies with the regulations, and the legal agent or thechild (≥8 years old) jointly sign the informed consent

Exclusion Criteria:

(1) Acute bacterial otitis media; (2) Patients with periodontitis or periodontal abscess (3) Candidiasis; (4) Patients with positive mycoplasma; (5) Taking antibiotics,anti-inflammatory drugs, and antihistamines; (6) Patients with severe comorbidities ofheart, liver and kidney; (7) Other patients with acute infectious diseases and mycoplasmapneumoniae infections with symptoms similar to upper respiratory tract infection; (8)Children with a history of epilepsy or convulsions; (9) Patients with mental illness; (10)Those who are allergic to treatment drugs; (11) Participated in other clinical trials inthe past month; (12) The investigator evaluates that it is not suitable to participate inthis clinical trial or according to the investigator's judgment, who is likely to loss tofollow-up.