Phase
Condition
Memory Loss
Mental Disability
Memory Problems
Treatment
ASCEND-I
Clinical Study ID
Ages 30-89 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Patient admitted for a stroke and accepted to acute inpatient rehabilitation atNYP-Weill Cornell.
Age 30-89
English speaking
Ability to comprehend sufficiently to participate in the treatment
Mild-moderate cognitive impairment as determined by a standard of care cognitivescreening tools administered by occupational therapists (e.g., Montreal CognitiveAssessment, Symbol-Digit Modalities Test, or other clinical standard of careinstrument). We will review subjects' most recent cognitive assessment administeredby OT (Occupational Therapists) and available in the EMR (Electronic MedicalRecords) to determine eligibility.
Willingness to participate in full study duration
Physically able to operate a computer keyboard, tablet/iPad, and mouse.
Exclusion
Exclusion Criteria:
History of other neurologic disorder (e.g., Parkinson's disease, Multiple Sclerosis,Alzheimer's disease, brain tumor). History of previous stroke(s) will not beexclusionary as long as the subject does not self-report having lasting/persistentcognitive impairment from the prior stroke.
History of severe mental illness (e.g., schizophrenia, psychosis) or substance usedisorder, recent history (in the past year) of alcohol/substance use disorder orsymptoms of psychosis. Note that the presence of post-stroke depression will not begrounds for exclusion.
History of dementia
Moderate-severe hemispatial neglect as determined by OT evaluation
Any factor that in the investigator's opinion is likely to compromise the subject'sability to participate in the study, including evidence that the subject may notunderstand and/or adhere to study requirements
Study Design
Connect with a study center
Weill Cornell Medicine
New York, New York 10065
United StatesSite Not Available
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