Transcranial Magnetic Stimulation in Progressive Supranuclear Palsy

Inclusion Criteria:

• probable or possible PSP by the revised MDS PSP Criteria (Hoglinger 2017)

• age 40-85 at time of screening

• ability to understand and cooperate with simple instructions in English

• ability to read at 6th grade reading level in English

• ability to stand unassisted for at least 30 seconds and to be able walkindependently with a walker

• ability to refrain from new physical and speech therapy programs for the duration ofthe study

• ability to remain on stable doses of any cholinergic, dopaminergic, serotonergicsedative or NMDA receptor antagonists for the duration of the study

• females of child-bearing age must perform a urine pregnancy test and be on reliablebirth control during the course of the study

Exclusion Criteria:

• other significant neurological or vestibular disorders

• presence of electrically, magnetically or mechanically activated implants or historyof injurious metal exposure in eyes, head, or body