Manuka Honey Eye Drops VS Conventional Treatment of Meibomian Gland Dysfunction Related Dry Eye Disease

Last updated: July 2, 2020
Sponsor: Chinese University of Hong Kong
Overall Status: Completed

Phase

4

Condition

Sjogren's Syndrome

Dry Eye Disease

Eyelid Inflammation

Treatment

N/A

Clinical Study ID

NCT04457648
MGD1
  • Ages > 18
  • All Genders

Study Summary

Assessor-masked (Single blind, randomized controlled trial comparing the conventional treatment group to an interventional group using 16% Manuka Honey topical eye drops.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • meibomian gland dysfunction stage 2-4

Exclusion

Exclusion Criteria:

  • <18 years old Unable to consent Recent ophthalmic surgery <6m Abnormalities of lidposition Allergy to honey/bee products Contact lens wearers Patients on long termtopical medications apart from lubricants

Study Design

Total Participants: 59
Study Start date:
June 01, 2018
Estimated Completion Date:
June 01, 2020

Study Description

Purpose To evaluate the effects of conventional treatment compared to use of Manuka Honey eye drops in the treatment of meibomian gland dysfunction related dry eye disease.

Design Assessor-masked (Single blind, randomized controlled trial comparing the conventional treatment group to an interventional group using 16% Manuka Honey topical eye drops.

Methods Patients were randomized into two groups, one group given conventional treatment for meibomian gland dysfunction. The other group was given additional manuka honey 16% eye drops which are registered as a medical device by the australian FDA. SPEED score was taken at baseline and upon follow up. Multiple parameters were graded from slit lamp examination by a masked assessor. Results were compared from baseline to follow up date 3 weeks later.

Connect with a study center

  • chinese university of Hong kong

    Hong Kong,
    China

    Site Not Available

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