A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

Phase

N/A

Condition

Obesity

Neoplasms

Weight Loss

Treatment

Media Intervention

Text Message

Telephone-Based Intervention

Clinical Study ID

NCT04453072

19-001992

NCI-2020-02687

Ages 13-30
All Genders
Accepts Healthy Volunteers

Study Summary

This early phase I trial studies how well a behavioral weight loss intervention consisting of a smartphone application and coaching works for the promotion of weight loss in adolescents and young adults after a stem cell transplant. This study may help researchers learn more about how adolescents and young adults can lose weight and develop healthy eating habits.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patients with a history of HSCT of any type, at least 100 days post-transplant atinitial consultation of the study, will be eligible for the study
Patients must classify as obese, represented as body mass index (BMI) >= 85thpercentile for age and gender
Patients must also be able to read English since the app intervention is onlyavailable in English form
No patients will be excluded for any specific underlying medical condition, butdecisions will be made on a case by case basis if a patient's functioning is deemedto significantly interfere with intervention participation
PARENT:
His/her child meets all inclusion criteria
>= 18 years of age
Can speak English

Exclusion

Exclusion Criteria:

Patients who are < 100 days post-transplant at initial consultation will not beeligible for the study, but may become eligible if they are > 100 dayspost-transplant at their next consultation that falls within the enrollment window
Patients whose BMI does not fall under the obese category will be excluded

Study Design

Media Intervention

July 01, 2020

December 31, 2026

Study Description

PRIMARY OBJECTIVE:

I. To evaluate the effectiveness of an addiction-based weight loss intervention, embodied as a smartphone application (app) with telephone coaching, on weight outcomes of overweight and obese post hematopoietic stem cell transplantation (HSCT) adolescents and young adults.

SECONDARY OBJECTIVES:

I. To evaluate the changes in metabolic parameters and physical activity levels, in addition to modifications in addictive eating behaviors, motivation, and self-regulatory behaviors.

II. To evaluate the feasibility, adherence, and satisfaction of this intervention.

OUTLINE:

Patients receive an iPhone with W8Loss2Go app, a body scale and a digital food scale to weigh themselves and food daily. Patients interact with coaches via text messages for 4 days weekly and receive weekly 15 minute phone calls for appointment reminders, emotional support, progress discussion, and follow up on items discussed in a prior visit or phone call. Patients also have telemedicine interviews with the coach lasting 60 minutes at 2 and 4 months to elicit both positive and negative impacts on weight management and to identify barriers such as emotional eating, displacement behaviors, poor coping skills to life stressors, and social challenges. Patients who opt to extend the intervention until month 12 attend an additional telemedicine meeting with the coach. Patients also complete questionnaires over approximately 1.5 hours.

Connect with a study center

UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California 90095
United States
Active - Recruiting

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