Carotid Risk Prediction (CRISP) Consortium

Last updated: February 3, 2021
Sponsor: Elucid Bioimaging Inc.
Overall Status: Active - Recruiting

Phase

N/A

Condition

Atherosclerosis

Carotid Artery Disease

Treatment

N/A

Clinical Study ID

NCT04448353
CRISP
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Develop adverse event prediction and plaque phenotype classification models for patients with known or suspected carotid artery disease.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Subjects must have two (or more) neck CTAs at least 6 months apart of sufficientquality as documented in the vascuCAP Reading Manual.
  • Atherosclerotic plaque must be visualized within the carotid artery.

Exclusion

Exclusion Criteria:

  • Subjects without visible plaque within the carotid artery
  • Subject with insufficient CTA image quality (defined strictly as documented in thevascuCAP Reading Manual)

Study Design

Total Participants: 800
Study Start date:
March 01, 2019
Estimated Completion Date:
April 30, 2022

Study Description

Develop adverse event prediction and plaque phenotype classification models using plaque morphology and composition assessment of CTA which has been validated by histology, applied to representative cohort of patients. Generalizability of models is enhanced by using validated rather than only raw image inputs. Demographic, clinical, and outcome data is collected for enrolled patients as well as information on events and interventions.

Connect with a study center

  • Baltimore VA Medical Center

    Baltimore, Maryland 21201
    United States

    Active - Recruiting

  • University of Maryland, Baltimore

    Baltimore, Maryland 21201
    United States

    Active - Recruiting

  • Walter Reed National Military Medical Center

    Bethesda, Maryland 20814
    United States

    Active - Recruiting

  • Weill Cornell Medicine (Affiliated with New York Presbyterian Hospital)

    New York, New York 10065
    United States

    Active - Recruiting

  • University Hospital Harrington (Affiliated with Case Western Reserve University)

    Cleveland, Ohio 44106
    United States

    Active - Recruiting

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