Early Detection of Cardiac Damage by Two‑Dimensional Speckle Tracking Echocardiography After Thoracic Radiation Therapy

Inclusion Criteria:

• with malignant tumors

• will receive radiotherapy

• with cardiac exposure during the radiotherapy process

• could receive regular follow-up for 12 months

• written informed consent

Exclusion Criteria:

• satisfactory echocardiographic images could not be obtained

• moderate or severe valvular disease

• cardiomyopathy

• congenital heart disease

• refractory hypertension

• coronary artery disease*

• heart failure

• arrhythmia requiring intervention

• pericarditis

• acute myocarditis

• participating in other clinical studies of drug intervention

• severe liver and kidney dysfunction

• autoimmune disease

• pulmonary hypertension coronary artery disease: at least 50% stenosis besed on previous coronary angiography orCTA, or with a history of percutaneous coronary stent implantation.

*: with LVEF<50%, unstable angina，or acute myocardial infarction within 3 months.