Effects of Barley Green in Patients With Hyperuricemia

Inclusion Criteria:

• Age 18-65 years old those who are willing to accept assessment and sign informedconsent.
• Under the normal purine diet, two fasting blood uric acid levels on different days: 420umol/l

Exclusion Criteria:

• Patients currently receiving treatment for hyperuricemia；
• Suffering from diseases that affect the digestion and absorption(such as chronicdiarrhea, constipation, severe gastrointestinal inflammation, active gastrointestinalulcers, after gastrointestinal resection, cholecystitis/cholecystectomy, etc.)；
• Suffering from cardiovascular and cerebrovascular diseases, grade 3 hypertension,chronic hepatitis, malignant tumors, anemia, mental illness and memory disorders,epilepsy and other diseases;
• At the same time receive other functional food nutrition support (plant activesubstances, health food);
• Patients with abnormal liver function (alanine aminotransferase or/and aspartateaminotransferase exceeds 3 times the upper limit of normal value); patients withabnormal renal function (serum creatinine exceeds the upper limit of normal value)；
• Suffering from infectious diseases such as active tuberculosis and AIDS;
• People who are severely allergic to the ingredients of research；
• During pregnancy or lactation;
• Patients with physical disabilities and clinicians think it is not suitable toparticipate in the study (for example, suffering from serious diseases not included inthe discharge criteria)；
• Gouty arthritis attack ≥ 2 times;
• One episode of gouty arthritis with blood uric acid >480 umol/l, or any of thefollowing: age <40 years old, evidence of gout stone or urate deposition in the jointcavity, uric acid nephrolithiasis or renal impairment (GFR≤89ml/(min·1.73m2)),hypertension, impaired glucose tolerance or diabetes, dyslipidemia, obesity, coronaryheart disease, stroke, cardiac insufficiency;
• Blood uric acid>480 umol/l combined with any of the following: uric acidnephrolithiasis or renal impairment (GFR≤89ml/(min·1.73m2)), hypertension, impairedglucose tolerance or diabetes, dyslipidemia, obesity, Coronary heart disease, stroke,heart failure.