Efficacy of Hyaluronic-acid and Hydrogen-Peroxide Mouthwash in Gingivitis Treatment

Last updated: June 16, 2020
Sponsor: University of Milan
Overall Status: Active - Not Recruiting

Phase

3

Condition

Hemorrhage

Periodontitis

Treatment

N/A

Clinical Study ID

NCT04438421
BMG0703_ORC_May 2019 v.0
  • Ages 12-50
  • All Genders

Study Summary

A clinical study to evaluate the efficacy and safety of a mouthwash containing Hydrogen Peroxide, Sodium Hyaluronate and Glycine in the prevention and management of complications associated gingivitis by film forming action.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Subjects aged between 12 and 50 years

  • Presence of gingivitis caused by accumulation of plaque/tartar

  • Acceptance of informed consent

Exclusion

Exclusion Criteria:

  • subjects suffering from HIV

  • subjects suffering from hepatitis

  • serious systemic diseases preventing the use of specific dental therapies

  • acute and/or chronic infectious diseases

  • inability to provide consent

  • use of topical or systemic drugs

  • inability to follow post-intervention hygiene instructions

  • smokers

Study Design

Total Participants: 50
Study Start date:
June 01, 2020
Estimated Completion Date:
July 31, 2020

Study Description

50 subjects will be enrolled, who show with gingivitis caused by accumulation of plaque and/or tartar selected consecutively. Subsequently, subjects will be equally divided and randomized into the test group or control group.

During the three examinations, the subjects will undergo the collection of bleeding and plaque indices according to Silness J & Loe H 3,4. Four surfaces per tooth (vestibular, lingual/palatal, mesial, distal) will be considered.

Connect with a study center

  • UOC Maxillofacial Surgery and Odontology, University of Milan

    Milan, Lombardy 20122
    Italy

    Site Not Available

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