Evaluation of Desensitization Therapy and Re-treatment of Eye Movement Information [EMDR] in Patients With Post-traumatic Stress Disorder [PTSD]

Last updated: February 8, 2023
Sponsor: Centre hospitalier de Ville-Evrard, France
Overall Status: Active - Recruiting

Phase

N/A

Condition

Anxiety Disorders

Post-traumatic Stress Disorders

Panic Disorders

Treatment

N/A

Clinical Study ID

NCT04431765
10477M-ICE-EMDR
  • Ages 18-65
  • All Genders

Study Summary

This research aims to confirm that the therapeutic effect of EMDR is associated with changes in the interaction between cognitive function and emotional stimuli in PTSD patients compared to a controlled therapy in a randomized, single-blind study.On the other hand, this study aims to observe neuronal and cognitive correlates related to EMDR therapy compared to a control therapy.

This investigation would improve the understanding of the mechanisms of action of the EMDR, still unknown to date.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patient diagnosed with PTSD according to DSM 5 criteria (APA 2013) related to a singletraumatic event,
  • Aged 18 to 65 years,
  • Signed informed consent.
  • Patient with social security affiliation or State Medical Aid (AME)

Exclusion

Exclusion Criteria:

  • Neurological disorders
  • No other major psychiatric disorders than PTSD (DSM 5)
  • Severe and/or unstable somatic pathologies,
  • Patient not affiliated with social security,
  • Patient hospitalized under stress in psychiatric care at the decision of the staterepresentative or in psychiatric care at the request of a third party,
  • Patient under guardianship,
  • Patient participating in parallel with other biomedical research,
  • Change of antidepressant during the last three months,
  • Patient not fluent in French
  • MR-specific criteria for not inclusion:
  • women of childbearing age without effective contraception or a positive pregnancytest,
  • patients carrying pacemakers or electrical or electronic devices, clips or metalprostheses,
  • subjects with neurological disorders, cerebral abnormalities or suffering fromclaustrophobia.

Study Design

Total Participants: 48
Study Start date:
July 02, 2018
Estimated Completion Date:
February 01, 2026

Connect with a study center

  • Ch Ville Evrard

    Neuilly-sur-Marne, 93330
    France

    Active - Recruiting

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