Senior-COVID-Rea Multicentric Survey

Last updated: July 28, 2020
Sponsor: Hospices Civils de Lyon
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT04422340
69HCL20_0386
  • Ages > 60
  • All Genders

Study Summary

With the spread of COVID-19 epidemic since 2019 in Wuhan, China health plans have to be adapted continuously in response to the emergency. The first publications from the Chinese experience demonstrate an increase in the incidence of COVID-19 infections in patients over 60 years of age, a higher frequency of severe forms of the disease and therefore theoretical indications of orientation towards resuscitative care.

However, the first published data from Hubei province suggest a low benefit of resuscitation for patients between 70 and 80 years of age and null in patients over 80 years of age. These data question the individual benefit / risk balance of an orientation towards resuscitation for this category of patients, their quality of life and the concept of unreasonable obstinacy.

Among the covariates associated with resuscitation mortality described in the data published to date, cardiovascular comorbidities, certain biological covariates (LDH, creatinine, lymphocytes, neutrophils, TP, D-dimers, etc.), the time between the first symptoms and the entry into resuscitation have been identified.

The objective of this multicentric observational study is to determine the clinical and biological covariates predictive of mortality in the population of patients over 60 years of age admitted in intensive care unit, in particular by integrating functional and nutritional data from patients 1 month before COVID-19 infection.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patient over 60

  • sent to the intensive care unit

  • whose COVID diagnosis has been established (RT-PCR and / or chest scanner)

Exclusion

Exclusion Criteria:

  • Refusal of the patient or his support person to participate in the study

Study Design

Total Participants: 185
Study Start date:
April 01, 2020
Estimated Completion Date:
August 15, 2020

Connect with a study center

  • Resuscitation unit at Hospital Emile Roux

    Le Puy-en-Velay,
    France

    Active - Recruiting

  • - Resuscitation unit of the Groupement Hospitalier Nord - Hospices Civils de Lyon

    Lyon,
    France

    Active - Recruiting

  • - Resuscitation unit of the Groupement Hospitalier Sud - Hospices Civils de Lyon

    Lyon,
    France

    Active - Recruiting

  • Resuscitation unit of the Groupement Hospitalier Centre - Hospices Civils de Lyon

    Lyon,
    France

    Active - Recruiting

  • Resuscitation unit of the Groupement Hospitalier Sud - Hospices Civils de Lyon

    Lyon,
    France

    Active - Recruiting

  • Service de Réanimation de l'Hôpital Nord Ouest

    Villefranche-sur-Saône,
    France

    Active - Recruiting

  • Medipole Resuscitation unit

    Villeurbanne, 69603
    France

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.