Treatment of Eustachian Tube Dysfunction (ETD) and Facial Pain With Combined Acoustic Vibration and Oscillating Expiratory Pressure

AIM 1

Inclusion Criteria:

• Adults 18 years or older with no symptoms of URI, ETD or other ENT conditions

Exclusion Criteria:

• Sinonasal or ear surgery within last 3 months (including balloon ET dilation)

• Any ENT condition that may impact upper airway to include sinusitis, otitis, orallergies

• Upper respiratory illness within last 2 weeks

• Topical decongestant use in last week

• Current nasal crusting or ulceration on rhinoscopy

• History of severe nose bleeding within last 3 months

• Known pregnancy

• Allergic sensitivity to silicone or any other component of device

• Inability to read and understand English

• Inability to perform treatment due to underlying medical condition

AIM 2

Inclusion:

• Adults 18 years or older with diagnosis of ETD by an otolaryngologist

• ≥6 months of symptoms duration

• ≥3 ETD symptoms (ear pressure, feeling that ears are clogged, cracking/popping ofears, muffled hearing, tinnitus)

• ETDQ-7 score ≥ 3

• Audiogram within the last year

Exclusion:

• Sinonasal or ear surgery within last 3 months (including balloon ET dilation)

• Indwelling ear tubes

• Tympanic membrane perforation

• Hx of cholesteatoma, mastoidectomy, tympanoplasty, or ossicular chain reconstruction

• Patulous ET

• Hx of Meniere's disease

• Moderate or severe nasal valve collapse

• Grade 3-4 polyps

• Upper respiratory illness within last 2 weeks

• Topical decongestant use in last week

• Current nasal crusting or ulceration on rhinoscopy

• History of severe nose bleeding within last 3 months

• Known pregnancy

• Allergic sensitivity to silicone or any other component of device

• Inability to read and understand English

• Inability to perform treatment due to underlying medical condition

AIM 3

Inclusion:

• Adults 18 years or older who complain of facial pain or pressure

• ≥3 months of symptoms duration (can be intermittent)

• Pain/pressure VAS score ≥ 5

Exclusion:

• Sinonasal surgery within the last 3 months

• Grade 3-4 polyps

• Upper respiratory illness within last 2 weeks

• Topical decongestant use in last week

• Current nasal crusting or ulceration on rhinoscopy

• History of severe nose bleeding within last 3 months

• Known pregnancy

• Allergic sensitivity to silicone or any other component of device

• Inability to read and understand English

• Inability to perform treatment due to underlying medical condition