Surgery Alone Versus Methotrexate Before Surgery in Cesarean Scar Pregnancy

Last updated: May 4, 2020
Sponsor: Mansoura University
Overall Status: Active - Recruiting

Phase

4

Condition

Scar Tissue

Treatment

N/A

Clinical Study ID

NCT04379219
R.19.10.639.R1.R2.R3
  • Female

Study Summary

There are no universal treatment guidelines available. The ultimate purpose of the management of CSP is to simultaneously remove the pregnancy and successfully preserve the woman's fertility (Gonzalez & Tulandi, 2017). A variety of medical and surgical treatment modalities for CSP have been reported; however, most of these are based on low‐level evidence(Sun et al., 2019).

Eligibility Criteria

Inclusion

Inclusion Criteria:•

  • Gestational age before 13 w

  • Past history of 1 or more CS

  • Presence of GS implanted on cesareans scar

Exclusion

Exclusion Criteria:

  • Presence of severe vaginal bleeding (emergency)

  • Previous history of uterine surgery other than CS

  • The whole mass is interior and the bulge is more in the cavity

  • Bleeding disorder

  • Patient not candidate for methotrexate (Positive fetal heart pulsation,

  • Patient refuse to participate in the study

Study Design

Total Participants: 56
Study Start date:
December 01, 2019
Estimated Completion Date:
December 31, 2020

Study Description

This will be a randomized clinical trial to evaluate the effect of administration of methotrexate before surgery in reducing bleeding, injury to bladder and ureter, operative time and removing of CSP mass.This will be in comparison to surgery alone in cases of first trimester cesarean scar pregnancy

Connect with a study center

  • Mansoura University

    Mansoura, Dakahliya
    Egypt

    Active - Recruiting

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