Proton Radiation Therapy Registry

Last updated: June 30, 2025
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Registry

Clinical Study ID

NCT04376229
J2008
IRB00228501
  • Ages 18-100
  • All Genders

Study Summary

The Johns Hopkins Proton Therapy center is establishing a registry to capture the full 3D radiation dosimetry delivered to the patient, baseline clinical data, and disease, toxicity and quality of life outcomes. The goal is to have all patients treated at the proton center to be included in the registry to enable future comparisons of treatment outcomes to assist in understanding which patients can benefit from the use of protons.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • All patients treated at the proton center.

Exclusion

Exclusion Criteria:

  • Any other than what is supplied in the inclusion criteria

Study Design

Total Participants: 5000
Treatment Group(s): 1
Primary Treatment: Registry
Phase:
Study Start date:
April 07, 2020
Estimated Completion Date:
December 31, 2040

Study Description

Proton based radiation therapy has considerable dosimetric advantages over the standard photon based radiation therapy, with a significantly higher cost. The clinical advantages, however, may not be realized for all patient populations, even with the improved dose distributions. Establishing the clinical efficacy of proton therapy requires years of experience treating patients. The goal is to accelerate the knowledge gain through the use of the registry that allows for detailed information to be captured and is inclusive of every patient treated.

Connect with a study center

  • Sibley Memorial Hospital

    Washington, District of Columbia 20016
    United States

    Active - Recruiting

  • Suburban Hospital

    Washington, District of Columbia 20814
    United States

    Active - Recruiting

  • Bayview Hospital

    Baltimore, Maryland 21224
    United States

    Active - Recruiting

  • Johns Hopkins Hospital

    Baltimore, Maryland 21287
    United States

    Active - Recruiting

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