Dimensional and Developmental Profiles of Psychosis in Children and Adolescents

Inclusion Criteria for the Patient:

1. Children and young adults ages 7-20 years with age of onset of psychotic disorderbetween 7-17 years.

2. Hospitalized or seen for out-patient treatment for a psychotic episode, acute orchronic.

3. DSM-V diagnosis of schizophrenia, schizoaffective disorder, schizophreniformdisorder, brief psychotic disorder, psychotic disorder not otherwise specified, ormajor depressive episode with psychotic features.

4. Written informed consent signed by the parents or the individual(s) with legalparental authority, and by the minor patient if his/her condition permits.

5. Written informed consent signed by the patient if he/she is a major, after clinicalstabilization (not delusional).

6. Has health insurance coverage from Social Security (France) (not AME coverage).

Inclusion Criteria for parents or siblings wishing to participate in the genetic part of the study :

1. Parents : no specific criteria.

2. Siblings : siblings are eligible to participate if there are at least twofirst-degree relatives with psychotic disorders (including the patient) in thefamily.

3. Written informed consent for the genetic part of the study signed by anyparticipating parents and siblings.

4. Has health insurance coverage from Social Security (France) (not AME coverage).

Exclusion Criteria:

1. Moderate or severe intellectual deficiency (IQ < 50).

2. Psychoses judged to be secondary to medical illness, medication effects or drugs ofabuse.

3. Diagnosis of bipolar disorder.

4. Patients who are under legal guardianship.

5. For the neuroimaging part of the study only : any contraindications to MagneticResonance Imaging.