Different PEEP Settings of COVID-19 Induced ARDS

Last updated: April 21, 2020
Sponsor: Southeast University, China
Overall Status: Completed

Phase

N/A

Condition

Lung Injury

Covid-19

Acute Respiratory Distress Syndrome (Ards)

Treatment

N/A

Clinical Study ID

NCT04359251
COVID-19 PEEP titration
  • Ages 18-80
  • All Genders

Study Summary

This was a multi-center prospective study. All consecutive severe cases of COVID-19 whose PO2/FiO2<300mmHg with invasive ventilation admitted to 5 fixed-point receive COVID-19 patients hospitals in Wuhan from 5 March to 15 March 2020 were included. Epidemiological, clinical data, lung mechanics, artery blood gas test and hemodynamics at three methods to titrate PEEP, optimizing oxygenation, optimizing compliance, ARDSnet. The study was approved by the Ethics Committee of Zhongda Hsopital, Southeast University.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • COVID-19 patients with mechanical ventilation

  • PO2/FIO2<300mmHg

  • ages>18 years

Exclusion

Exclusion Criteria:

  • pneumothorax

  • pregnant

  • hemodynamics is unstable

Study Design

Total Participants: 20
Study Start date:
March 05, 2020
Estimated Completion Date:
March 25, 2020

Study Description

After PEEP titration, PEEP settings could be set by optimizing oxygenation, optimizing compliance, ARDSnet.

Connect with a study center

  • Zhongda Hospital, Southeast University

    Nanjing, Jiangsu 210009
    China

    Site Not Available

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