Does Medical Cannabis Reduce Opioid Use in Adults With Pain

Inclusion Criteria:

• At least 18 years of age
• English or Spanish fluency
• Actively certified for medical cannabis
• Intends to have a soft-gel capsule product dispensed at Vireo
• Medical cannabis qualifying conditions or complications of "chronic or severe pain" or "pain that degrades health and functional capability as an alternative to opioid useor substance use disorder"
• Joint or neuropathic pain
• Current severe pain
• Dispensed opioid analgesics within the last 60 days To maintain the integrity of the study, we do not disclose all inclusion criteria topotential participants.

Exclusion Criteria:

• Inability to provide informed consent
• Inability to complete study visits over 14 weeks
• Terminal illness
• Current or prior psychotic disorder
• Buprenorphine or methadone treatment for opioid use disorder within the past year
• Allergies to tapioca or coconut
• Currently pregnant, planning to become pregnant within the next 3 months, orbreastfeeding
• Condition that is considered by a pharmacist or medical provider to be acontraindication to medical cannabis use (e.g. unstable cardiac arrhythmia or specificdrug-use interaction)