Clinical Trial to Assess the Efficacy and Safety of MUCOLASE Tablet(Streptokinase • Streptodornase)

Inclusion Criteria:

• 19≤ age

• Patients with acute upper respiratory infection or acute bronchitis

• Patients with cough and phlegm within 48 hrs as of Visit 1

• Patients understood the consents and purpose of this trial and signed consent form

Exclusion Criteria:

• Patients with high fever (≥39℃)

• Patients with severe respiratory diseases (ex) bronchial asthma, pneumonia, pulmonarytuberculosis, bronchiectasis, mucus sticking, chronic obstructive pulmonary disease (COPD), etc.

• Patients with a history of hypersensitivity to drug

• Patients with abnormal blood coagulation

• Patients with thrombocytopenia

• Patients with uncontrolled hypertension

• Patients with a severe liver disorder(AST or ALT level exceeds 2 times more thannormal upper range)

• Patients woth a clinically significant renal failure(MDRD eGFP < 60 mL/min/1.73m2)