Carpal Tunnel Syndrome and Amyloidosis

Last updated: January 27, 2020
Sponsor: Corporacion Parc Tauli
Overall Status: Active - Recruiting

Phase

N/A

Condition

Amyloidosis

Carpal Tunnel Syndrome

Treatment

N/A

Clinical Study ID

NCT04245098
CSPT_AMICAR1
  • All Genders

Study Summary

Carpal tunnel syndrome has been suggested to be an early sign of amyloidosi. The investigators will evaluate tissue samples obtained from patients undergoing carpal tunnel release surgery for amyloid.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients undergoing carpal tunnel syndrome surgery

Exclusion

Exclusion Criteria:

  • None

Study Design

Total Participants: 100
Study Start date:
January 08, 2020
Estimated Completion Date:
January 08, 2023

Study Description

Carpal tunnel syndrome (CTS) can be caused by the deposition and accumulation of misfolded proteins called amyloid and is often an early manifestation of systemic amyloidosis.

Patients with cardiac amyloidosis often have carpal tunnel syndrome that precedes cardiac manifestations by several years, and many patients will have undergone surgery for idiopathic carpal tunnel syndrome since the protein also deposits in the transversal carpal ligament of the hand.

The investigators sought to identify the prevalence and type of amyloid deposits in patients undergoing carpal tunnel surgery and evaluate for cardiac involvement

Connect with a study center

  • Maria Del Carmen Navarro-Saez

    Sabadell, Barcelona 08208
    Spain

    Active - Recruiting

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