Effect of rTMS on the Abnormal Executive Function of ASD Children

Inclusion Criteria:

• Patients diagnosed with ASD. Diagnostic criteria: diagnosed by pediatric psychiatristsin accordance with the criteria in the Fifth Edition of Diagnostic and StatisticalManual of Mental Disorders (DSM-V), Autism Diagnostic Observation Schedule (ADOS) andAutism Diagnostic Interview-Revised (ADI-R);

• Have a diagnosis of high functioning ASD (HF-ASD) (i.e., are verbal with anIntelligence Quotient (IQ) ≥ 70)

• Are clinically stable as determined by their treating physician, with no medicationchanges over the past 4 weeks

Exclusion Criteria:

• Have metal or electronic instruments near the stimulation brain area of coil, such as,have intravascular stent in head, have metal objects in skull.

• Have cardiac pacemaker, cochlear implant, medical pump;

• Can not cooperate with examiner;

• Have intracranial foreign bodies by craniotomy, or intracranial deformity

• Have a history of substance abuse or dependence in the last 6 months or have apositive urine toxicology screen

• Have a concomitant major medical or neurologic illness

• Have had a seizure in the past, or have a first-degree relative with epilepsy

• Have an abnormal clinical EEG

• Are pregnant or likely to get pregnant during the next 4 weeks

• Have a history of rTMS treatment.